The Effect of Neighborhood Disadvantage on the Racial Disparity in Ovarian Cancer-Specific Survival in a Large Hospital-Based Study in Cook County, Illinois
| Autor: | Timothy P. Johnson, Caryn E. Peterson, Charlotte E. Joslin, Seijeoung Kim, Marian L. Fitzgibbon, Richard E. Barrett, Sally Freels, Garth H. Rauscher, Carolyn V. Kirschner, Faith G. Davis |
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| Rok vydání: | 2015 |
| Předmět: |
Gerontology
Racial disparity Neighborhood Disadvantage Negative association survival analysis Hospital based study 03 medical and health sciences 0302 clinical medicine medicine ovarian cancer and socioeconomic status 030212 general & internal medicine Survival analysis Original Research Concentrated Disadvantage business.industry lcsh:Public aspects of medicine Public Health Environmental and Occupational Health lcsh:RA1-1270 medicine.disease Debulking healthcare disparities racial disparities in ovarian cancer 3. Good health 030220 oncology & carcinogenesis Public Health neighborhood effect Ovarian cancer business Demography |
| Zdroj: | Frontiers in Public Health Frontiers in Public Health, Vol 3 (2015) |
| ISSN: | 2296-2565 |
| DOI: | 10.3389/fpubh.2015.00008 |
| Popis: | This paper examines the effect of neighborhood disadvantage on racial disparities in ovarian cancer-specific survival. Despite treatment advances for ovarian cancer, survival remains shorter for African-American compared to White women. Neighborhood disadvantage is implicated in racial disparities across a variety of health outcomes and may contribute to racial disparities in ovarian cancer-specific survival. Data were obtained from 581 women (100 African-American and 481 White) diagnosed with epithelial ovarian cancer between June 1, 1994, and December 31, 1998 in Cook County, Illinois, which includes the city of Chicago. Neighborhood disadvantage score at the time of diagnosis was calculated for each woman based on Browning and Cagney’s index of concentrated disadvantage. Cox proportional hazard models measured the association of self-identified African-American race with ovarian cancer-specific survival after adjusting for age, tumor characteristics, surgical debulking, and neighborhood disadvantage. There was a statistically significant negative association (-0.645) between ovarian cancer-specific survival and neighborhood disadvantage (p = 0.008). After adjusting for age and tumor characteristics, African-American women were more likely than Whites to die of ovarian cancer (HR = 1.59, p = 0.003). After accounting for neighborhood disadvantage, this risk was attenuated (HR = 1.32, p = 0.10). These findings demonstrate that neighborhood disadvantage is associated with ovarian cancer-specific survival and may contribute to the racial disparity in survival. |
| Databáze: | OpenAIRE |
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