Interactions between Oxidative Stress, Lipid Profile and Antioxidants in Breast Cancer: A Case Control Study
| Autor: | Chitrangada Shrivastav, Siddharth Mehra, Rajni Kumari, Seema Chugh, Amit Kumar Patel, Ajay Narayan Sharma, Rakesh K. Gupta |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Cancer Research
medicine.medical_specialty Epidemiology Breast Neoplasms Nitric Oxide medicine.disease_cause Antioxidants Lipid peroxidation chemistry.chemical_compound Breast cancer Malondialdehyde Internal medicine medicine Humans Triglycerides Unsaturated fatty acid chemistry.chemical_classification Glutathione Peroxidase medicine.diagnostic_test Superoxide Dismutase business.industry Glutathione peroxidase Public Health Environmental and Occupational Health Cancer Middle Aged medicine.disease Lipids Lipoproteins LDL Oxidative Stress Cholesterol Endocrinology Oncology chemistry Case-Control Studies Immunology Female Lipoproteins HDL Lipid profile business Oxidative stress |
| Zdroj: | Asian Pacific Journal of Cancer Prevention. 13:6295-6298 |
| ISSN: | 1513-7368 |
| DOI: | 10.7314/apjcp.2012.13.12.6295 |
| Popis: | Oxidant/antioxidant balance has been suggested as an important factor for initiation and progression of cancer. The objective of this study was to determine changes in the levels of malondialdehyde (MDA), nitric oxide (NO), total cholesterol, triglycerides, LDL-cholesterol, HDL-cholesterol, total antioxidant capacity (TAC), glutathione peroxidase (GSH-Px), and superoxide dismutase (SOD) activities in serum samples of breast cancer patients (n=30) and healthy subjects (n=100). MDA and NO levels were found to be increased in breast cancer patients compared to the healthy subject group (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|