Smoking and the risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition
Autor: | Rudolf Kaaks, Kim Overvad, N. Larrañaga, Rosario Tumino, Paer Stattin, Antonio Agudo, Margareta Johansson, H. J. Van Kranen, Anders Bjartell, Anne Tjønneland, Antonia Trichopoulou, M-D Chirlaque, Domenico Palli, Hendriek C. Boshuizen, Jakob Linseisen, Aurelio Barricarte, H. B. Bueno-de-Mesquita, Elio Riboli, Pagona Lagiou, Dimitrios Trichopoulos, N. F. Johnsen, Heiner Boeing, Marc J. Gunter, Sabine Rohrmann, Vittorio Krogh, Tobias Pischon, David Ulmert, Fulvio Ricceri, Naomi E. Allen, Kay-Tee Khaw, Nicholas J. Wareham, M-J Sanchez, Birgit Teucher, Isabelle Romieux, Pietro Ferrari, Timothy J. Key, M. V. Argüelles Suárez |
---|---|
Přispěvatelé: | University of Zurich, Rohrmann, S |
Jazyk: | angličtina |
Rok vydání: | 2013 |
Předmět: |
Male
Cancer Research Nutrition and Disease Epidemiology Wiskundige en Statistische Methoden - Biometris Prostate cancer 0302 clinical medicine Risk Factors Surveys and Questionnaires Voeding en Ziekte follow-up 1306 Cancer Research Prospective Studies Registries 030212 general & internal medicine Prospective cohort study Smoking Prostate Cancer Cohort Study Epic Incidence Incidence (epidemiology) cohort Middle Aged Prognosis prostate cancer 3. Good health European Prospective Investigation into Cancer and Nutrition Europe Survival Rate 030220 oncology & carcinogenesis Cohort 2730 Oncology Life Sciences & Biomedicine Cohort study Adult medicine.medical_specialty recurrence Nutritional Status men 610 Medicine & health tobacco use Risk Assessment smoking 03 medical and health sciences Internal medicine medicine cohort study Humans ddc:610 Survival rate Mathematical and Statistical Methods - Biometris Gynecology Science & Technology health-professionals prospective us business.industry cigarette-smoking association Prostatic Neoplasms 10060 Epidemiology Biostatistics and Prevention Institute (EBPI) medicine.disease ONCOLOGY mortality business EPIC Follow-Up Studies |
Zdroj: | British Journal of Cancer, 108(3), 708-714 Rohrmann, S, Linseisen, J, Allen, N, Bueno-de-Mesquita, H B, Johnsen, N F, Tjønneland, A, Overvad, K, Kaaks, R, Teucher, B, Boeing, H, Pischon, T, Lagiou, P, Trichopoulou, A, Trichopoulos, D, Palli, D, Krogh, V, Tumino, R, Ricceri, F, Argüelles Suárez, M V, Agudo, A, Sánchez, M-J, Chirlaque, M-D, Barricarte, A, Larrañaga, N, Boshuizen, H, van Kranen, H J, Stattin, P, Johansson, M, Bjartell, A, Ulmert, D, Khaw, K-T, Wareham, N J, Ferrari, P, Romieux, I, Gunter, M J R, Riboli, E & Key, T J 2013, ' Smoking and the risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition ', B J C, vol. 108, no. 3, pp. 708-14 . https://doi.org/10.1038/bjc.2012.520 Br. J. Cancer 108, 708-714 (2013) British Journal of Cancer 108 (2013) 3 British Journal of Cancer |
ISSN: | 0007-0920 |
Popis: | Background:Smoking is not associated with prostate cancer incidence in most studies, but associations between smoking and fatal prostate cancer have been reported.Methods:During 1992 and 2000, lifestyle information was assessed via questionnaires and personal interview in a cohort of 145 112 European men. Until 2009, 4623 incident cases of prostate cancer were identified, including 1517 cases of low-grade, 396 cases of high grade, 1516 cases of localised, 808 cases of advanced disease, and 432 fatal cases. Multivariable Cox proportional hazards regression models were used to examine the association of smoking status, smoking intensity, and smoking duration with the risk of incident and fatal prostate cancer.Results:Compared with never smokers, current smokers had a reduced risk of prostate cancer (RR=0.90, 95% CI: 0.83-0.97), which was statistically significant for localised and low-grade disease, but not for advanced or high-grade disease. In contrast, heavy smokers (25+ cigarettes per day) and men who had smoked for a long time (40+ years) had a higher risk of prostate cancer death (RR=1.81, 95% CI: 1.11-2.93; RR=1.38, 95% CI: 1.01-1.87, respectively).Conclusion:The observation of an increased prostate cancer mortality among heavy smokers confirms the results of previous prospective studies.British Journal of Cancer advance online publication, 20 November 2012; doi:10.1038/bjc.2012.520www.bjcancer.com. |
Databáze: | OpenAIRE |
Externí odkaz: |