Smoking and the risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition

Autor: Rudolf Kaaks, Kim Overvad, N. Larrañaga, Rosario Tumino, Paer Stattin, Antonio Agudo, Margareta Johansson, H. J. Van Kranen, Anders Bjartell, Anne Tjønneland, Antonia Trichopoulou, M-D Chirlaque, Domenico Palli, Hendriek C. Boshuizen, Jakob Linseisen, Aurelio Barricarte, H. B. Bueno-de-Mesquita, Elio Riboli, Pagona Lagiou, Dimitrios Trichopoulos, N. F. Johnsen, Heiner Boeing, Marc J. Gunter, Sabine Rohrmann, Vittorio Krogh, Tobias Pischon, David Ulmert, Fulvio Ricceri, Naomi E. Allen, Kay-Tee Khaw, Nicholas J. Wareham, M-J Sanchez, Birgit Teucher, Isabelle Romieux, Pietro Ferrari, Timothy J. Key, M. V. Argüelles Suárez
Přispěvatelé: University of Zurich, Rohrmann, S
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Male
Cancer Research
Nutrition and Disease
Epidemiology
Wiskundige en Statistische Methoden - Biometris
Prostate cancer
0302 clinical medicine
Risk Factors
Surveys and Questionnaires
Voeding en Ziekte
follow-up
1306 Cancer Research
Prospective Studies
Registries
030212 general & internal medicine
Prospective cohort study
Smoking
Prostate Cancer
Cohort Study
Epic
Incidence
Incidence (epidemiology)
cohort
Middle Aged
Prognosis
prostate cancer
3. Good health
European Prospective Investigation into Cancer and Nutrition
Europe
Survival Rate
030220 oncology & carcinogenesis
Cohort
2730 Oncology
Life Sciences & Biomedicine
Cohort study
Adult
medicine.medical_specialty
recurrence
Nutritional Status
men
610 Medicine & health
tobacco use
Risk Assessment
smoking
03 medical and health sciences
Internal medicine
medicine
cohort study
Humans
ddc:610
Survival rate
Mathematical and Statistical Methods - Biometris
Gynecology
Science & Technology
health-professionals
prospective us
business.industry
cigarette-smoking
association
Prostatic Neoplasms
10060 Epidemiology
Biostatistics and Prevention Institute (EBPI)
medicine.disease
ONCOLOGY
mortality
business
EPIC
Follow-Up Studies
Zdroj: British Journal of Cancer, 108(3), 708-714
Rohrmann, S, Linseisen, J, Allen, N, Bueno-de-Mesquita, H B, Johnsen, N F, Tjønneland, A, Overvad, K, Kaaks, R, Teucher, B, Boeing, H, Pischon, T, Lagiou, P, Trichopoulou, A, Trichopoulos, D, Palli, D, Krogh, V, Tumino, R, Ricceri, F, Argüelles Suárez, M V, Agudo, A, Sánchez, M-J, Chirlaque, M-D, Barricarte, A, Larrañaga, N, Boshuizen, H, van Kranen, H J, Stattin, P, Johansson, M, Bjartell, A, Ulmert, D, Khaw, K-T, Wareham, N J, Ferrari, P, Romieux, I, Gunter, M J R, Riboli, E & Key, T J 2013, ' Smoking and the risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition ', B J C, vol. 108, no. 3, pp. 708-14 . https://doi.org/10.1038/bjc.2012.520
Br. J. Cancer 108, 708-714 (2013)
British Journal of Cancer 108 (2013) 3
British Journal of Cancer
ISSN: 0007-0920
Popis: Background:Smoking is not associated with prostate cancer incidence in most studies, but associations between smoking and fatal prostate cancer have been reported.Methods:During 1992 and 2000, lifestyle information was assessed via questionnaires and personal interview in a cohort of 145 112 European men. Until 2009, 4623 incident cases of prostate cancer were identified, including 1517 cases of low-grade, 396 cases of high grade, 1516 cases of localised, 808 cases of advanced disease, and 432 fatal cases. Multivariable Cox proportional hazards regression models were used to examine the association of smoking status, smoking intensity, and smoking duration with the risk of incident and fatal prostate cancer.Results:Compared with never smokers, current smokers had a reduced risk of prostate cancer (RR=0.90, 95% CI: 0.83-0.97), which was statistically significant for localised and low-grade disease, but not for advanced or high-grade disease. In contrast, heavy smokers (25+ cigarettes per day) and men who had smoked for a long time (40+ years) had a higher risk of prostate cancer death (RR=1.81, 95% CI: 1.11-2.93; RR=1.38, 95% CI: 1.01-1.87, respectively).Conclusion:The observation of an increased prostate cancer mortality among heavy smokers confirms the results of previous prospective studies.British Journal of Cancer advance online publication, 20 November 2012; doi:10.1038/bjc.2012.520www.bjcancer.com.
Databáze: OpenAIRE
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