Iodine 125 Seed for Localization in Primary Hyperparathyroidism
| Autor: | Theo Adriaensen, Hans K. S. Nuytinck, Sophie J. R. de Danschutter, Jennifer M. J. Schreinemakers, Paul D. Gobardhan, Peter A. M. Kint, Lijckle van der Laan |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Pilot Projects Scintigraphy 030218 nuclear medicine & medical imaging Iodine Radioisotopes 03 medical and health sciences 0302 clinical medicine Preoperative Care medicine Humans Minimally Invasive Surgical Procedures Radionuclide Imaging Netherlands Parathyroidectomy medicine.diagnostic_test business.industry Ultrasound Ultrasonography Doppler Middle Aged Hyperparathyroidism Primary medicine.disease Iodine 125 seed Surgery Endocrine surgery Treatment Outcome Image-guided surgery medicine.anatomical_structure Surgery Computer-Assisted 030220 oncology & carcinogenesis Feasibility Studies Female Parathyroid gland Radiology business Complication Primary hyperparathyroidism Follow-Up Studies |
| Zdroj: | Surgical Innovation. 23:593-597 |
| ISSN: | 1553-3514 1553-3506 |
| DOI: | 10.1177/1553350616663323 |
| Popis: | Background. Preoperative localization of the parathyroid gland prior to a minimally invasive parathyroidectomy (MIP) is important because of varying locations of the parathyroid gland. Several methods have been described to localize the affected gland. One novel technique is the use of an iodine 125 (I-125) seed as a marker. The aim of this study is to evaluate the feasibility of using an I-125 seed in localizing the diseased parathyroid gland prior to MIP. Materials and methods. This is a pilot study of 10 patients performed in the Amphia Hospital, the Netherlands. Patients in whom primary hyperparathyroidism (PHPT) was diagnosed in combination with 1 enlarged parathyroid gland on ultrasound (US) and scintigraphy and who were eligible for MIP were included in this study. These patients underwent a preoperative US-guided I-125 seed placement in the affected parathyroid gland. The main study parameters were the feasibility of the placement, intraoperative localization of the diseased gland and complications. Results. A total of 10 patients were included. The US-guided I-125 placement in the affected parathyroid gland was technically feasible in the majority of cases. Because of the anatomical location of the gland, the placement was difficult in 2 patients, resulting in suboptimal position and possible misplacement of the marker. MIP was uncomplicated in most cases. Complications during surgery were mainly intraoperative bleeding. Conclusions. The use of an I-125 seed for preoperative localization in PHPT is a relatively safe technique in parathyroid surgery. More research is needed to compare this technique with other preoperative localization techniques. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|