Of Fighting Flies, Mice, and Men: Are Some of the Molecular and Neuronal Mechanisms of Aggression Universal in the Animal Kingdom?
| Autor: | Shaun M. Davis, Amanda L. Thomas, Herman A. Dierick |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Cancer Research
Injury control Transcription Genetic lcsh:QH426-470 Accident prevention Poison control Receptors Cytoplasmic and Nuclear Review Toxicology 03 medical and health sciences Mice 0302 clinical medicine Neuronal control Genetics medicine Animals Humans Animal behavior Molecular Biology Genetics (clinical) Ecology Evolution Behavior and Systematics 030304 developmental biology Neurons 0303 health sciences Potential impact biology Behavior Animal Aggression Neuropeptides biology.organism_classification Biological Evolution lcsh:Genetics Drosophila melanogaster Evolutionary biology medicine.symptom 030217 neurology & neurosurgery |
| Zdroj: | PLoS Genetics, Vol 11, Iss 8, p e1005416 (2015) PLoS Genetics |
| ISSN: | 1553-7404 1553-7390 |
| Popis: | Aggressive behavior is widespread in the animal kingdom, but the degree of molecular conservation between distantly related species is still unclear. Recent reports suggest that at least some of the molecular mechanisms underlying this complex behavior in flies show remarkable similarities with such mechanisms in mice and even humans. Surprisingly, some aspects of neuronal control of aggression also show remarkable similarity between these distantly related species. We will review these recent findings, address the evolutionary implications, and discuss the potential impact for our understanding of human diseases characterized by excessive aggression. |
| Databáze: | OpenAIRE |
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