Non-selective His bundle pacing with a biphasic waveform: enhancing septal resynchronization
| Autor: | Analia Paolucci, Emilio Logarzo, Daniel Felipe Ortega, Maria Paula Bonomini, Nicolas Mangani, Luis D. Barja |
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| Rok vydání: | 2017 |
| Předmět: |
Male
Bundle of His medicine.medical_specialty Bundle-Branch Block Argentina MEDLINE 030204 cardiovascular system & hematology Outcome assessment Cardiac Resynchronization Therapy Electrocardiography 03 medical and health sciences 0302 clinical medicine His bundle pacing Physiology (medical) Internal medicine Outcome Assessment Health Care Severe conduction disturbances medicine Humans 030212 general & internal medicine Aged business.industry Stroke Volume Stroke volume Biphasic waveform Middle Aged Echocardiography Bundle Anesthesia Cardiology Female Resynchronization Cardiomyopathies Electrophysiologic Techniques Cardiac Cardiology and Cardiovascular Medicine business |
| Zdroj: | EP Europace. 20:816-822 |
| ISSN: | 1532-2092 1099-5129 |
| DOI: | 10.1093/europace/eux098 |
| Popis: | Aims: His bundle pacing has shown to prevent detrimental effects from right ventricular apical pacing (RVA) and proved to resynchronize many conduction disturbances cases. However, the extent of His bundle pacing resynchronization is limited. An optimized stimulation waveform could expand this limit when implemented in His bundle pacing sets. In this work, we temporarily implemented RVA and Non-selective His bundle pacing with a biphasic anodal-first waveform (AF-nHB) and compared their effects against sinus rhythm (SR). Methods and results: Fifteen patients referred for electrophysiologic study with conduction disturbances, cardiomyopathy and ejection fraction below 35% were enrolled for the study. The following acute parameters were measured: QRS duration, left ventricular activation (RLVT), time of isovolumic contraction (IVCT), ejection fraction (EF), and dP/dtmax. QRS duration and RLVT decreased markedly under AF-nHB (SR: 169 ± 34 ms vs. nHB: 116 ± 31 ms, P |
| Databáze: | OpenAIRE |
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