Association between periodontal condition and the development of type 2 diabetes mellitus-Results from a 15-year follow-up study

Autor: Tuomas Saxlin, Sirkka Keinänen-Kiukaanniemi, Sirpa S. Anttila, Pekka Ylöstalo, Matti Knuuttila, Ville Myllymäki, Ulla Rajala
Rok vydání: 2018
Předmět:
Zdroj: Journal of clinical periodontology. 45(11)
ISSN: 1600-051X
1990-1992
Popis: Aim To study whether periodontal condition is associated with the development of type 2 diabetes mellitus (T2DM). Materials and methods A population-based follow-up study was conducted among persons born in 1935 and living in the city of Oulu, Finland (n = 395). The baseline examinations were done during 1990-1992, and the follow-up examinations were done during 2007-2008. The data were gathered by questionnaires, laboratory tests and clinical measurements. Poisson regression models were used in the data analyses. Results The adjusted rate ratios (RR) with 95% confidence intervals (95% CI) for the incident T2DM among subjects with 4-5 mm deep periodontal pockets (n = 98), among subjects with 6 mm deep or deeper periodontal pockets (n = 91), and among edentulous subjects (n = 118) were 1.32 (95% CI: 0.69-2.53), 1.56 (95% CI: 0.84-2.92) and 1.00 (95% CI: 0.53-1.89), respectively, compared to dentate subjects without deepened (4 mm deep or deeper) periodontal pockets (n = 88). The adjusted RR per site (the number of sites with deepened periodontal pockets as a continuous variable) was 1.02 (95% CI: 1.00-1.04). Conclusions Poor periodontal condition may be a predictor of the development of T2DM. However, the causality between periodontal condition and the development of T2DM remains uncertain.
Databáze: OpenAIRE
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