First isolation of Sarcocystis neurona from the South American opossum, Didelphis albiventris, from Brazil
| Autor: | Benjamin M. Rosenthal, C. E. Kerber, Nobuko Kasai, Hilda Fátima de Jesus Pena, S. K. Shen, David S. Lindsay, Jitender P. Dubey, Oliver C.H. Kwok, Solange Maria Gennari |
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| Rok vydání: | 2001 |
| Předmět: |
Pathology
medicine.medical_specialty South American opossum Antibodies Protozoan Sarcocystosis Polymerase Chain Reaction Equine protozoal myeloencephalitis Didelphis albiventris Interferon-gamma Mice parasitic diseases medicine Animals Parasite hosting Mice Knockout Mice Inbred BALB C General Veterinary biology Brain Sarcocystis Opossums General Medicine DNA Protozoan Isolation (microbiology) biology.organism_classification Virology Intestines Sarcocystis neurona South american Parasitology Brazil |
| Zdroj: | Veterinary Parasitology. 95:295-304 |
| ISSN: | 0304-4017 |
| Popis: | Sarcocystis neurona was isolated from sporocysts from two of eight South American opossums, Didelphis albiventris, from Brazil. Interferon gamma gene knock out (KO) mice fed sporocysts from two opossums developed neurologic sarcocystosis. S. neurona was demonstrated in the brains of infected KO mice by immunohistochemical staining with anti-S. neurona antibody. The parasite was cultivated in cell culture and S. neurona DNA was isolated from cultured merozoites. This is the first report of isolation of S. neurona from Brazil and the first report from its new host, D. albiventris. |
| Databáze: | OpenAIRE |
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