Four-Year Prospective Study of Homosexual Men: Correlation of Immunologic Abnormalities, Clinical Status, and Serology to Human Immunodeficiency Virus
| Autor: | Rosalyn E. Stahl, Michael Marmor, Stanley H. Weiss, Wafaa El-Sadr, Susan Zolla-Pazner, Sam D'Onofrio, Daniel William, Margaret Lyden, W. Carl Saxinger |
|---|---|
| Rok vydání: | 1987 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Constitutional symptoms T-Lymphocytes Human immunodeficiency virus (HIV) Disease HIV Antibodies Antibodies Viral medicine.disease_cause Asymptomatic Serology Acquired immunodeficiency syndrome (AIDS) AIDS-Related Complex Internal medicine medicine Humans Immunology and Allergy Prospective Studies Prospective cohort study Acquired Immunodeficiency Syndrome business.industry HIV Homosexuality Middle Aged medicine.disease Disease control Infectious Diseases Immunoglobulin G Immunology medicine.symptom beta 2-Microglobulin business |
| Zdroj: | Journal of Infectious Diseases. 155:789-793 |
| ISSN: | 1537-6613 0022-1899 1981-1985 |
| DOI: | 10.1093/infdis/155.4.789 |
| Popis: | Infection with human immunodeficiency virus (HIV; formerly called HTLV-III/LAV), like many other infectious diseases, is associated with a wide spectrum of disease manifestations. Some individuals infected with HIV have remained asymptomatic, while others have developed mild constitutional symptoms, severe signs of disease, or AIDS, as defined by the Centers for Disease Control (CDC, Atlanta, Ga) [1]. The factors that influence the development of the various clinical manifestations remain largely unknown. To elucidate factors that may influence the clinical outcome of HIV infection, we initiated a prospective study of a group of men at high risk for acquiring this infection. We report here on 40 randomly selected, homosexual men from New York City, who were studied over a four-year period (1981-1985) and were evaluated serologically, immunologically, and clinically on an individual basis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|