Supplementary Figures 1 - 5 from Complement C5a Receptor Facilitates Cancer Metastasis by Altering T-Cell Responses in the Metastatic Niche

Autor: Maciej M. Markiewski, Magdalena Karbowniczek, Othon Almanza, Wojciech Gorczyca, David P. Fairlie, Sasikanth Manne, Linley Riediger, Clayton Cleveland, Priya Sharma, Sharad K. Sharma, Navin K. Chintala, Surya Kumari Vadrevu
Rok vydání: 2023
DOI: 10.1158/0008-5472.22404072
Popis: PDF file - 981KB, Liver metastasis, C5aR expression on myeloid, 4T1 and T cells, infiltration of CD8+ T cells and MDSCs in livers of breast tumor-bearing mice (S1). MDSCs infiltrate lungs of breast tumor bearing mice prior to metastases (S2). Complement production and activation in tumor bearing mice and C5aR expression in lymph nodes of breast cancer patients (S3). Gating for regulatory T (Treg) cells (S4). Gating for cytokine producing myeloid cells (S5).
Databáze: OpenAIRE