Mucinous appendiceal neoplasms with or without pseudomyxoma peritonei: a review
| Autor: | Mikael L. Soucisse, Mohammad S. Alshahrani, Joshua Lansom, David L. Morris |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Mitomycin Disease 03 medical and health sciences 0302 clinical medicine medicine Pseudomyxoma peritonei Humans Peritoneal Neoplasms business.industry Optimal treatment General surgery General Medicine Cytoreduction Surgical Procedures Hyperthermia Induced medicine.disease Pseudomyxoma Peritonei Optimal management Appendiceal neoplasms Appendiceal Neoplasms Curative treatment 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology Surgery Hyperthermic intraperitoneal chemotherapy Histopathology business |
| Zdroj: | ANZ journal of surgeryReferences. 90(10) |
| ISSN: | 1445-2197 |
| Popis: | Mucinous appendiceal neoplasms (MANs) are rare tumours and the primary cause of pseudomyxoma peritonei. These tumours have a much more benign course than typical colorectal cancers, generally growing for many years before giving any clinical signs. The spectrum of presentations, tumour stages and the underlying cytology is very wide, warranting from the simplest operation like an appendicectomy to the most complicated operation like a complete cytoreduction surgery and hyperthermic intraperitoneal chemotherapy. Fortunately, most patients can be offered a curative treatment, but limiting operative morbidity without compromising oncologic outcomes is the biggest challenge in managing these patients. Histopathology is the cornerstone of decision making for MANs, but is also subject to ongoing debate because of a lack of terminology consensus amongst pathologists. Combined with the rarity of this disease, the multiple histopathologic classification updates of MANs explain the ongoing confusion amongst clinicians in regard to individual optimal treatment. This review will cover the most recent histological classification of MANs and attempt to clarify optimal management of patients with different clinical presentation and histologic combinations. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text