Dural involvement in primary extradural meningiomas of the cranial vault
Autor: | Dietmar Stolke, Siamak Asgari, Uwe Hübschen, Hischam Bassiouni, Hermann-Josef König |
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Rok vydání: | 2006 |
Předmět: |
Adult
Male medicine.medical_specialty Dura mater medicine.medical_treatment Radiography Skull Neoplasms Malignancy Meningioma Cranial vault Meningeal Neoplasms Humans Medicine Neoplasm Invasiveness Craniotomy Aged Retrospective Studies Aged 80 and over medicine.diagnostic_test business.industry Ectopic Meningioma Magnetic resonance imaging Middle Aged medicine.disease Surgery Treatment Outcome medicine.anatomical_structure Female Dura Mater business Follow-Up Studies |
Zdroj: | Journal of Neurosurgery. 105:51-59 |
ISSN: | 0022-3085 |
Popis: | Object The authors retrospectively analyzed a consecutive series of patients with cranial vault primary extradural meningioma (PEM), with particular regard to the tumor’s dural involvement. The pertinent literature was reviewed. Methods Clinical data were retrospectively obtained in a consecutive series of 16 patients treated for a PEM at two institutions between 1992 and 2004. The authors created a classification system based on dural involvement of the tumors. Nine women and six men (mean age 55 years) presented with a painless, slowly progressive swelling. Preoperative magnetic resonance (MR) imaging revealed dural enhancement at the site of tumor in 11 patients. On surgical inspection, the tumor infiltrated the dura in all but three patients. Histological examination of tissue samples demonstrated tumor infiltration of the dura in all 14 patients in whom the dura had been resected. Three recurrent tumors were observed on follow-up examination during a mean period of 5.8 years (range 1.5–13 years) and required extirpation. In addition to one patient in whom there was histological evidence of malignancy, the other two cases involved two patients in whom no apparent dural involvement was observed during the first surgery. In a review of the literature, the authors found that histological examination showed dural involvement in 22%; the dura was not histologically evaluated in the remaining patients (78%). Postoperative follow-up data exceeding 2 years were only provided in two of the reported cases. Conclusions Tumor infiltration of the dura should be assumed in PEMs of the cranial vault, and resection of the dura at the site of craniotomy is recommended to prevent tumor recurrence. |
Databáze: | OpenAIRE |
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