Recurrent or first preeclampsia in multiparae: A case-control study of singleton pregnancies in Reunion Island
Autor: | Asma Omarjee, Chloé Schweizer, Pierre-Yves Robillard, Silvia Iacobelli, Malik Boukerrou, Coralie Dumont, Phuong Lien Tran |
---|---|
Rok vydání: | 2019 |
Předmět: |
Adult
medicine.medical_specialty Perinatal Death Gestational Age Severity of Illness Index Preeclampsia 03 medical and health sciences symbols.namesake 0302 clinical medicine Pre-Eclampsia Pregnancy Recurrence Risk Factors Epidemiology medicine Humans 030212 general & internal medicine Risk factor reproductive and urinary physiology Fisher's exact test First episode 030219 obstetrics & reproductive medicine Obstetrics Singleton business.industry Perinatal mortality Cesarean Section Case-control study Infant Newborn Pregnancy Outcome Obstetrics and Gynecology medicine.disease female genital diseases and pregnancy complications Reproductive Medicine Case-Control Studies Hypertension symbols Female business Reunion |
Zdroj: | European journal of obstetrics, gynecology, and reproductive biology. 240 |
ISSN: | 1872-7654 |
Popis: | Recurrent or first preeclampsia in multiparae : a case-control study of singleton pregnancies in Reunion Island Phuong Lien Tran, Pierre-Yves Robillard, Coralie Dumont, Chloé Schweizer, Asma Omarjee, Glorianne Lazaro, Silvia Iacobelli, Malik Boukerrou OBJECTIVE: To compare multiparous women with a first occurrence of preeclampsia and those with recurrent preeclampsia in singleton pregnancies.a 17.5-year (2001-2018) case-control study conducted in the University's maternity of South Reunion (Indian Ocean), comparing 125 patients with recurrent preeclampsia and 742 patients with a first episode of the disease (controls). Statistical analyses were performed with use of the Student t-test for comparison of continuous data and the Chi-square or Fisher exact test for comparison of categorical variables.There was no difference between the two groups concerning socio-demographic characteristics, post-partum haemorrhage, perinatal mortality rates. Nevertheless, recurrent preeclamptic women had a higher risk to present with prior chronic hypertension (OR 2.05 [1.30-3.23], p = 0.002), and to experience an early onset preeclampsia (34 weeks) compared to controls (OR 1.69 [1.15-2.48], p = 0.007). Women with recurrent preeclampsia were more prone to have C-sections (OR 1.63 [1.06-2.51], p = 0.024) mainly because of maternal indications (89.2% vs 76.4%, p = 0.008). Newborns from recurrent preeclampsia were more likely to have very low birthweight1500 g (OR 1.79 [1.16-2.77], p = 0.001), while there was no significant difference for gestational ages (34.1 vs 34.7 weeks).Recurrent multiparous preeclamptic women presented more severe maternal disease (with a higher rate of early onset preeclampsia). Persistent hypertension in women with a history of preeclampsia is a risk factor for developing recurrent preeclampsia, and these patients should be monitored more closely. |
Databáze: | OpenAIRE |
Externí odkaz: |