Anorectal Chlamydia trachomatis Load Is Similar in Men Who Have Sex with Men and Women Reporting Anal Sex
| Autor: | Nicole H. T. M. Dukers-Muijrers, Petra F. G. Wolffs, Christian J. P. A. Hoebe, Geneviève A F S van Liere, Jeanne A. M. C. Dirks |
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| Přispěvatelé: | Med Microbiol, Infect Dis & Infect Prev, RS: CAPHRI School for Public Health and Primary Care, RS: CAPHRI - R4 - Health Inequities and Societal Participation |
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Sexual Behavior media_common.quotation_subject Anal Canal lcsh:Medicine Chlamydia trachomatis Biology medicine.disease_cause urologic and male genital diseases Men who have sex with men PHARYNGEAL CHLAMYDIA Young Adult Risk Factors medicine Humans Homosexuality Homosexuality Male Young adult lcsh:Science RECTAL CHLAMYDIA media_common Gynecology Multidisciplinary Chlamydia Obstetrics lcsh:R PERSISTENCE Transmission potential Chlamydia Infections Middle Aged Anal canal medicine.disease SWABS Bacterial Load female genital diseases and pregnancy complications PREVALENCE medicine.anatomical_structure Female lcsh:Q NEISSERIA-GONORRHOEAE SEXUALLY-TRANSMITTED INFECTION Anal sex Research Article |
| Zdroj: | PLOS ONE, 10(8):e0134991. Public Library of Science PLoS ONE, Vol 10, Iss 8, p e0134991 (2015) PLoS ONE |
| ISSN: | 1932-6203 |
| Popis: | BackgroundAnorectal Chlamydia trachomatis (chlamydia) is frequently diagnosed in men who have sex with men (MSM) and in women, but it is unknown whether these infections are comparable in clinical impact and transmission potential. Quantifying bacterial load and identifying determinants associated with high bacterial load could provide more insight.MethodsWe selected a convenience sample of MSM who reported anal sex (n = 90) and women with concurrent urogenital/anorectal chlamydia who reported anal sex (n = 51) or did not report anal sex (n = 61) from the South Limburg Public Health Service's STI unit. Bacterial load (Chlamydia/ml) was quantified for all samples and log transformed for analyses. Samples with an unquantifiable human leukocyte antigen (n = 9) were excluded from analyses, as they were deemed inadequately sampled.ResultsThe mean log anorectal chlamydia load (3.50) was similar for MSM and women who reported having anal sex (3.80, P = 0.21). The anorectal chlamydia load was significantly higher in these groups than in women who did not report having anal sex (2.76, P = 0.001). Detectable load values ranged from 1.81-6.32 chlamydia/ml for MSM, 1.74-7.33 chlamydia/ml for women who reported having anal sex and 1.84-6.31 chlamydia/ml for women who did not report having anal sex. Symptoms and several other determinants were not associated with anorectal chlamydia load.ConclusionsWomen who did not report anal sex had lower anorectal loads, but they were within a similar range to the other two groups. Anorectal chlamydia load was comparable between MSM and women who reported anal sex, suggesting similar transmission potential. |
| Databáze: | OpenAIRE |
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