Type-2 diabetes and cognitive function in a non-demented population
| Autor: | Matti Vanhanen, Leena Mykkänen, Paavo J. Riekkinen, Johanna Kuusisto, H. Soininen, Markku Laakso, Eeva-Liisa Helkala, Keijo Koivisto, T. Hänninen |
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| Rok vydání: | 2009 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty endocrine system diseases Population Type 2 diabetes Neuropsychological Tests Risk Factors Diabetes mellitus Internal medicine Activities of Daily Living medicine Humans Dementia education Aged education.field_of_study medicine.diagnostic_test nutritional and metabolic diseases Cognition General Medicine Neuropsychological test Intracranial Arteriosclerosis medicine.disease Executive functions Endocrinology Diabetes Mellitus Type 2 Neurology Frontal lobe Brain Damage Chronic Female Neurology (clinical) Cognition Disorders Mental Status Schedule Psychology Diabetic Angiopathies |
| Zdroj: | Acta Neurologica Scandinavica. 100:97-101 |
| ISSN: | 1600-0404 0001-6314 |
| DOI: | 10.1111/j.1600-0404.1999.tb01045.x |
| Popis: | Objectives - To study if type-2 (non-insulin-dependent) diabetes mellitus (NIDDM) is associated with cognitive dysfunction independently of clinically diagnosed dementia in an elderly population. Material and methods - Cognitive function was investigated with a brief neuropsychological test battery in a non-demented elderly population consisting of 183 NIDDM (World Health Organization, 1985) patients and 732 non-diabetic subjects. Results - Patients with NIDDM were impaired in the Trail-Making Test parts A and C, which may be a reflection of mildly affected frontal lobe/executive functions. Women with NIDDM performed better than non-diabetic subjects in the Mini-Mental State Examination. Conclusions - We conclude that NIDDM per se is not associated with impaired memory in the elderly, and the minor defects observed in tests of frontal lobe/executive functions are unlikely to affect daily living. In the non-demented population aged 69-78 years, NIDDM does not carry a significant risk of cognitive dysfunction, when compared to the non-diabetic subjects. |
| Databáze: | OpenAIRE |
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