Mucinous biliary cystadenoma with mesenchymal stroma: Expressions of CA 19-9 and carcinoembryonic antigen in serum and cystic fluid
| Autor: | Jau-Hong Lee, Shin-Cheng Pang, Dar-Ren Chen, Yih-Shyoung Lai |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
medicine.medical_specialty
Pathology CA-19-9 Antigen Diagnosis Differential Carcinoembryonic antigen Cystadenoma Mucinous Internal medicine Biomarkers Tumor medicine Humans biology business.industry Polycystic liver disease Liver Neoplasms Angiography Gastroenterology Middle Aged Hepatology medicine.disease Carcinoembryonic Antigen Biliary Tract Neoplasms Cystadenoma biology.protein Immunohistochemistry Female CA19-9 Differential diagnosis Tomography X-Ray Computed business Follow-Up Studies Abdominal surgery |
| Zdroj: | Journal of Gastroenterology. 31:732-736 |
| ISSN: | 1435-5922 0944-1174 |
| DOI: | 10.1007/bf02347626 |
| Popis: | A case of mucinous biliary cystadenoma with mesenchymal stroma (CMS tumor) in a 64-year-old woman is reported. The patient presented with acute abdominal pain and a palpable mass in the upper abdomen. Computed tomography and abdominal sonography showed characteristic multilocular cysts in the left lobe of the liver. Serum CA 19-9 was elevated to 108 U/ml with normal carcinoembryonic antigen (CEA) and alpha-fetoprotein (AFP) levels. The levels of CA 19-9 and CEA in the cystic fluid were high at 7430 U/ml and 576 ng/ml, respectively. The serum CA 19-9 returned to 35 U/ml 4 weeks after tumor resection. These corresponding findings of both tumor markers in the serum and cystic fluid imply that (1) CA 19-9 and CEA both exist in the epithelial component of CMS tumors as evidenced by immunohistochemical stain, (2) serum CA 19-9 is a valuable marker in the diagnosis and monitoring of CMS, and (3) in cystic fluid, there are more significantly high levels of CA 19-9 in CMS compared with levels in simple cyst and polycystic liver disease. Therefore, measurement of CA 19-9 in cystic fluid and serum may be helpful in the differential diagnosis of hepatic cystic lesions. |
| Databáze: | OpenAIRE |
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