Symptom-based questionnaire for differentiating COPD and asthma
| Autor: | Elizabeth F. Juniper, Mark L Levy, Thys van der Molen, Thomas Hausen, Constant P. van Schayck, Dmitry Nonikov, Robert J. Nordyke, David G. Tinkelman, David Price, Daryl Freeman, Anders Østrem, Sharon Isonaka, Ronald J. Halbert |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2006 |
| Předmět: |
Adult
Male Pulmonary and Respiratory Medicine Spirometry medicine.medical_specialty Colorado diagnosis EUROPEAN-COMMUNITY education spirometry GUIDELINES OBSTRUCTIVE PULMONARY-DISEASE Diagnosis Differential Pulmonary Disease Chronic Obstructive primary care MEDICATION Forced Expiratory Volume Surveys and Questionnaires Internal medicine GENERAL-PRACTICE Odds Ratio medicine Humans Prospective Studies Prospective cohort study chronic obstructive pulmonary disease (COPD) Aged Asthma validation studies COPD medicine.diagnostic_test business.industry Incidence Incidence (epidemiology) Respiratory disease Odds ratio Middle Aged asthma questionnaires medicine.disease Obstructive lung disease respiratory tract diseases PREVALENCE RESPIRATORY SYMPTOMS Scotland Physical therapy Female business |
| Zdroj: | Respiration, 73(3), 296-305. KARGER |
| ISSN: | 0025-7931 |
| Popis: | Background: Many patients with obstructive lung disease (OLD) carry an inaccurate diagnostic label. Symptom-based questionnaires could identify persons likely to need spirometry. Objectives: We prospectively tested questions derived from a comprehensive literature review and an international Delphi panel to help identify chronic OLD (COPD) in persons with prior evidence of OLD. Methods: Subjects were recruited via random mailing to primary-care practices in Aberdeen, Scotland, and Denver, Colorado. Persons aged 40 and older reporting any prior diagnosis of OLD or any respiratory medications in the past year were enrolled. Participants answered 54 questions covering demographics and symptoms and underwent spirometry with reversibility testing. A study diagnosis of COPD was defined by fixed airway obstruction as measured by post-bronchodilator FEV1/FVC Results: 597 persons completed all investigations and proceeded to analysis. The list of 54 questions yielded 52 items for analyses, which was reduced to 19 items for entry into a multivariate regression model. Nine items had significant relationships with the study diagnosis of COPD, including increased age, pack-years, worsening cough, breathing-related disability or hospitalization, worsening dyspnea, phlegm quantity, cold going to the chest, and receipt of treatment for breathing. Individual items yielded odds ratios ranging from 0.33 to 20.7. This questionnaire demonstrated a sensitivity of 72.0 and a specificity of 82.7. Conclusions: A short, symptom-based questionnaire identifies persons more likely to have COPD among persons with prior evidence of OLD. |
| Databáze: | OpenAIRE |
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