Aryl Ether as a Negishi Coupling Partner: An Approach for Constructing CC Bonds under Mild Conditions

Autor:	Chao Wang, Masanobu Uchiyama, Takashi J. Ozaki, Ryo Takita
Rok vydání:	2012
Předmět:	chemistry.chemical_classification Negishi coupling Aryl Organic Chemistry Ether General Chemistry Medicinal chemistry Catalysis chemistry.chemical_compound chemistry Reagent Functional group Organic chemistry Reactivity (chemistry) Alkyl Zincate
Zdroj:	Chemistry - A European Journal. 18:3482-3485
ISSN:	0947-6539
DOI:	10.1002/chem.201103784
Popis:	An etheric Negishi coupling: The first cross-coupling reaction between aryl alkyl ethers and dianion-type zincate reagents to afford biaryl compounds through selective cleavage of the etheric C(sp(2))-O bond was developed. Dianion-type zincates showed excellent reactivity toward the aromatic ethers under mild conditions, with good functional group compatibility (see scheme).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e6afcd708ae92994f7432db1cbe204e https://doi.org/10.1002/chem.201103784 Zobrazit plný text záznamu Plný text