A window into the future? MRI for evaluation of neuromyelitis optica spectrum disorder throughout the disease course
| Autor: | Friedemann Paul, Claudia Chien, Jiwon Oh, Dalia L. Rotstein, Jacqueline M. Solomon |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Advances in Neuroimaging medicine.medical_specialty NMOSD Disease Review Disease course 03 medical and health sciences 0302 clinical medicine medicine Spectrum disorder Subclinical disease RC346-429 Pharmacology Neuromyelitis optica medicine.diagnostic_test business.industry Optimal treatment Magnetic resonance imaging Disease monitoring medicine.disease 030104 developmental biology Neurology Neurology. Diseases of the nervous system Neurology (clinical) Radiology prognosis business disease activity 030217 neurology & neurosurgery MRI |
| Zdroj: | Therapeutic Advances in Neurological Disorders Therapeutic Advances in Neurological Disorders, Vol 14 (2021) |
| ISSN: | 1756-2856 |
| Popis: | Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing, inflammatory disease of the central nervous system marked by relapses often associated with poor recovery and long-term disability. Magnetic resonance imaging (MRI) is recognized as an important tool for timely diagnosis of NMOSD as, in combination with serologic testing, it aids in distinguishing NMOSD from possible mimics. Although the role of MRI for disease monitoring after diagnosis is not as well established, MRI may provide important prognostic information and help differentiate between relapses and pseudorelapses. Increasing evidence of subclinical disease activity and the emergence of newly approved, highly effective immunotherapies for NMOSD adjure us to re-evaluate MRI as a tool to guide optimal treatment selection and escalation throughout the disease course. In this article we review the role of MRI in NMOSD diagnosis, prognostication, disease monitoring, and treatment selection. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|