Influence of androgen levels on conception probability in patients undergoing fertility treatment: a retrospective cohort study
| Autor: | Mariz Kasoha, L Stotz, Sebastian Findeklee, Erich-Franz Solomayer, Iulian Iordache, Julia Caroline Radosa, Romina Sima, P Sklavounos, Carolin Spüntrup, Fabinshy Thangarajah |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
medicine.medical_specialty Sterility medicine.drug_class media_common.quotation_subject Reproductive medicine Fertility Young Adult 03 medical and health sciences 0302 clinical medicine Pregnancy medicine Humans Androstenedione Testosterone Probability Retrospective Studies media_common 030219 obstetrics & reproductive medicine business.industry Obstetrics Obstetrics and Gynecology Retrospective cohort study General Medicine Middle Aged Androgen Fertilization 030220 oncology & carcinogenesis Androgens Female Hyperandrogenism business Infertility Female Cohort study |
| Zdroj: | Archives of Gynecology and Obstetrics. 299:1481-1485 |
| ISSN: | 1432-0711 0932-0067 |
| Popis: | Primary and secondary sterility have become an issue of increasing importance due to demographic and social changes in society. Data regarding the association between female androgen levels and the probability of successful conception after fertility treatment are sparse and contradictive. This study was designed to assess this clinical question. In this retrospective single-center cohort study concentrations of androgens androstenedione, dehydroepiandrosteronsulfat (DHEAS) and testosterone (ng/ml) were investigated in the serum of patients presenting for sterility at the department of reproductive medicine of Saarland University hospital Homburg between January 2015 and December 2017. Androgen levels were correlated with reproductive outcomes. Statistical analysis was performed with the aid of SPSS version 24. Significance for conception rates in dependence of androgen concentration was assessed using Kruskal–Wallis test (significance was estimated with p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink