ALKALINE PHOSPHATASE ACTIVITY IN THE BONES OF NORMAL AND SCORBUTIC GUINEA PIGS

Autor:	E. M. Nadel, Anita Zorzoli
Rok vydání:	1953
Předmět:	Histology Biochemistry Chemistry Guinea Pigs Phosphatase Alkaline phosphatase Scurvy Anatomy Alkaline Phosphatase Bone and Bones Phosphoric Monoester Hydrolases
Zdroj:	Journal of Histochemistry & Cytochemistry. 1:362-371
ISSN:	1551-5044 0022-1554
DOI:	10.1177/1.5.362
Popis:	Alkaline phosphatase activity was measured in the tibias of normal and scorbutic guinea pigs. After twenty six days on a scorbutogenic diet the activity in the scorbutic had a mean value of 4.16 mg P/gm/hour in comparison to 8.04 mg P/gm/hour for the control group. Histochemical study of sections of the bones after demineralization revealed a decrease in the black precipitate indicative of phosphatase activity in the scorbutic bones. The decrease in precipitate was especially striking in the epiphyseal plate and in the metaphysis.
Databáze:	OpenAIRE
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