Factors influencing occurrence of peritonitis in Saudi children on peritoneal dialysis
| Autor: | Zahra Al Sannaa, Khamisa Al Mokali, Anwar E. Ahmed, Faten Al Mutairi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Percentile Adolescent medicine.medical_treatment Peritoneal dialysis 030232 urology & nephrology Saudi Arabia Peritonitis 030204 cardiovascular system & hematology 03 medical and health sciences symbols.namesake 0302 clinical medicine Risk Factors Internal medicine medicine Body Size Humans Poisson regression Poisson Distribution Child Retrospective Studies business.industry Acute kidney injury Age Factors lcsh:RJ1-570 Infant Retrospective cohort study lcsh:Pediatrics Guideline medicine.disease Confidence interval Anti-Bacterial Agents Child Preschool Pediatrics Perinatology and Child Health symbols Kidney Failure Chronic Nephrosis Female business Research Article |
| Zdroj: | BMC Pediatrics, Vol 20, Iss 1, Pp 1-7 (2020) BMC Pediatrics |
| ISSN: | 1471-2431 |
| Popis: | Background The peritonitis rate among children treated with peritoneal dialysis (PD) has not been widely reported in Saudi Arabia. The study aim was to estimate the peritonitis rate per patient-year and investigate the factors associated with higher peritonitis rates in a sample of PD children at King Abdullah Specialist Children’s Hospital-Riyadh (KASCH-R), Saudi Arabia. Methods This retrospective cohort study included 27 PD children treated between September 2007 and December 2017 at KASCH-R. We recorded the children’s demographic and clinical data, and the frequency of peritonitis. Results The 27 PD children reviewed (63% girls; mean age = 7.32 years old; range, 1–14 years), resulted in 86 peritonitis diagnoses in which the overall recurrence rate (in at least one episode) was 58/86 (67.4%) with a 95% confidence interval (CI), 56.5 to 77.2%. The rate of peritonitis episodes per patient-year was 0.76 (1 episode per 1.31 patient-year). The generalized Poisson model identified older children (age > 10 years) (adjusted rate ratios [aRR] = 7.273, 95% CI: 1.562–33.860), congenital nephrosis (aRR = 4.677, 95% CI: 1.443–15.155), height below 3rd percentile (aRR = 4.689, 95% CI: 1.874–11.735), weight below 3rd percentile (aRR = 5.388, 95% CI: 1.678–17.302), low albumin level (aRR = 4.041, 95% CI: 2.053–7.956), two-week duration of antibiotic therapy (aRR = 2.947, 95% CI: 1.163–7.468), which were independently associated with a high peritonitis rate. Conclusions This study showed a high peritonitis rate in our center. Older children, congenital nephrosis, height and weight below the 3rd percentile, low albumin level, and long duration of antibiotic therapy were associated with a higher rate of peritonitis. An optimal peritonitis prevention strategy or best-practice guideline is needed to reduce and prevent peritonitis occurrence in our center. |
| Databáze: | OpenAIRE |
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