Total serum protein reference value as a clinical diagnostic index of equine proliferative enteropathy
| Autor: | Satoshi Sekiguchi, Yosuke Sasaki, Ryoko Uemura, Masuo Sueyoshi, Toru Higuchi, Hidekazu Niwa, Yasushi Ueno |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
total serum protein Equine business.industry 020209 energy equine proliferative enteropathy 02 engineering and technology Note 021001 nanoscience & nanotechnology medicine.disease Gastroenterology Lawsonia intracellularis Proliferative enteropathy Hypoproteinemia Internal medicine Total serum protein 0202 electrical engineering electronic engineering information engineering Medicine 0210 nano-technology business Value (mathematics) Feces clinical diagnostic index |
| Zdroj: | Journal of Equine Science |
| ISSN: | 1347-7501 1340-3516 |
| Popis: | Equine proliferative enteropathy (EPE) caused by Lawsonia intracellularis is characterized by hypoproteinemia. There are currently no reliable reports that provide a reference value for the total serum protein (TP) concentration to clinically diagnose EPE. The objective of this study was to statistically determine the reference value. Feces and sera of 99 foals with EPE-like clinical signs and of 35 healthy foals were obtained. The samples were used for specific-gene detection of L. intracellularis, TP measurement, and specific-antibody detection against L. intracellularis. Based on these results, the optimal reference value for the TP concentration as a clinical diagnostic index of EPE was found to be ≤ 4.8 g/dl. This clinical diagnostic index will provide an effective approach for diagnosing EPE. |
| Databáze: | OpenAIRE |
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