Reuse of internal pulse generator in cases of infection after deep brain stimulation surgery
| Autor: | Abdullah Topcu, Aikaterini Panteli, Selcuk Gocmen, Feridun Acar, Ozkan Celiker, Göksemin Acar |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Male
Movement disorders medicine.medical_treatment retrospective study Deep Brain Stimulation reimplantation Generator recycling ethylene oxide data base device infection middle aged cost antibiotic therapy antibiotic agent prevention and control computer Aged Deep Brain Stimulation/adverse effects/*instrumentation Electrodes Implanted/adverse effects/*microbiology Equipment Contamination/prevention & control Equipment Reuse/standards Female Follow-Up Studies Humans Middle Aged Movement Disorders/diagnosis/*therapy Retrospective Studies Staphylococcal Infections/*diagnosis/*etiology instrument sterilization clinical article Movement Disorders Pulse generator adult Follow up studies article health care cost Staphylococcal Infections Electrodes Implanted aged female Anesthesia standards medicine.symptom Infection motor dysfunction pulse generator medicine.medical_specialty Deep brain stimulation water infection rate Hardware electrode implant medicine medical device contamination Equipment Reuse follow up human device removal cost control nonhuman business.industry medical device complication temperature economic aspect major clinical study Surgery incidence Equipment Contamination Neurology (clinical) brain depth stimulation business internal pulse generator Deep brain stimulation surgery |
| Popis: | Background: Hardware-related infection after deep brain stimulation (DBS) is one of the most serious complications and may need additional interventions. Objectives: To reuse the internal pulse generator (IPG) after DBS infection and to reduce the economic costs. Methods: A database of 102 patients who underwent DBS surgery was used in the study. The incidence, clinical characteristics and management of infections while reusing the IPG after DBS-related infection were analyzed and reported. Results: The overall infection rate was 5.9% (6 of 102 patients). Management consisted of total hardware removal followed by intravenous antibiotics. The IPG was at first kept in a solution, then rinsed with water and dried following sterilization with ethylene oxide gas at 38°C for 18 h. When the treatment of the infection was finished, we reused the IPG and reimplanted the DBS. No hardware-related infection or other complications were observed after reimplantation. Conclusions: Management of hardware-related infections can be challenging. The medical and economic costs associated with these infections are enormous. The IPG can often be saved in infected patients. Thus, a significant cost burden is eliminated. Properly executed, reuse of IPG should markedly reduce the costs of these devices. |
| Databáze: | OpenAIRE |
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