Short and long term perinatal outcome in twin pregnancies affected by weight discordance
| Autor: | Line Rode, C. Vedel, Helle Zingenberg, Lene Sperling, Lillian Skibsted, Eva-Christine Weiss, Birgit Bødker, Anna Oldenburg, Lone Krebs, Jeanette Tranberg Christensen, E. Krampl-Bettelheim, Stefan Hinterberger, Helle Larsen, Jan Ramb, Kirsten Riis Andreasen, I. Stornes, V. Ersbak, A. Holmskov, Niels Uldbjerg, Katharina Worda, Isolde Strobl, Lone Laursen, Ann Tabor |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Pediatrics Birth weight Infant Newborn Diseases Body Mass Index Cohort Studies 03 medical and health sciences 0302 clinical medicine Patient Admission Pregnancy Risk Factors Intensive care Intensive Care Units Neonatal Infant Mortality medicine Journal Article Chorionicity Birth Weight Humans 030212 general & internal medicine Labor Induced Risk factor Randomized Controlled Trials as Topic Retrospective Studies 030219 obstetrics & reproductive medicine Obstetrics business.industry Smoking Infant Newborn Obstetrics and Gynecology Gestational age Infant twins General Medicine Odds ratio medicine.disease neonatal complications Premature birth Ages and Stages Questionnaire Infant Small for Gestational Age Pregnancy Twin Small for gestational age Premature Birth Female business birthweight discordance Cohort study Follow-Up Studies |
| Zdroj: | Vedel, C, Oldenburg, A, Worda, K, Larsen, H, Holmskov, A, Andreasen, K R, Uldbjerg, N, Ramb, J, Bødker, B, Skibsted, L, Sperling, L, Hinterberger, S, Krebs, L, Zingenberg, H, Weiss, E-C, Strobl, I, Laursen, L, Christensen, J T, Ersbak, V, Stornes, I, Krampl-Bettelheim, E, Tabor, A & Rode, L 2017, ' Short and long term perinatal outcome in twin pregnancies affected by weight discordance ', Acta Obstetricia et Gynecologica Scandinavica, vol. 96, no. 2, pp. 233-242 . https://doi.org/10.1111/aogs.13062 Vedel, C, Oldenburg, A M, Worda, K, Larsen, H, Holmskov, A, Andreasen, K R, Uldbjerg, N, Ramb, J, Bødker, B, Skibsted, L, Sperling, L, Hinterberger, S, Krebs, L, Zingenberg, H, Weiss, E-C, Strobl, I, Laursen, L, Christensen, J T, Ersbak, V, Stornes, I, Krampl-Bettelheim, E, Tabor, A & Rode, L 2017, ' Short-and long-term perinatal outcome in twin pregnancies affected by weight discordance ', Acta Obstetricia et Gynecologica Scandinavica, vol. 96, no. 2, pp. 233-242 . https://doi.org/10.1111/aogs.13062 Vedel, C, Oldenburg, A, Worda, K, Larsen, H, Holmskov, A, Andreasen, K R, Uldbjerg, N, Ramb, J, Bødker, B, Skibsted, L, Sperling, L, Hinterberger, S, Krebs, L, Zingenberg, H, Weiss, E-C, Strobl, I, Laursen, L, Christensen, J T, Ersbak, V, Stornes, I, Krampl-Bettelheim, E, Tabor, A & Rode, L 2017, ' Short-and long-term perinatal outcome in twin pregnancies affected by weight discordance ', Acta Obstetricia et Gynecologica Scandinavica, vol. 96, no. 2, pp. 233-242 . https://doi.org/10.1111/aogs.13062 |
| DOI: | 10.1111/aogs.13062 |
| Popis: | INTRODUCTION: The objective was to investigate the association between chorionicity-specific intertwin birthweight discordance and adverse outcomes including long-term follow up at 6, 18, and 48-60 months after term via Ages and Stages Questionnaire.MATERIAL AND METHODS: In this secondary analysis of a cohort study (Oldenburg et al., n = 1688) and a randomized controlled trial (PREDICT study, n = 1045) twin pairs were divided into three groups according to chorionicity-specific birthweight discordance: 90th percentile. Information on infant mortality, admittance to neonatal intensive care units, and gestational age at delivery was available for all pairs. Detailed neonatal outcomes were available for 656 pairs from PREDICT, of which 567 pairs had at least one Ages and Stages Questionnair follow-up. Logistic regression models were used for dichotomous outcomes. Ages and Stages Questionnair scores were compared using the method of generalized estimating equation to account for the correlation within twins.RESULTS: The 75th and 90th percentiles for birthweight discordance were 14.8 and 21.4% for monochorionic and 16.0 and 23.8% for dichorionic twins. After adjustment for small for gestational age and gender, birthweight discordance >75th and >90th percentile was associated with induced delivery 75th-percentile was associated with an increased risk of infant mortality after 28 days [odds ratio 4.69 (95% confidence interval 1.07-20.45)] but not with major neonatal complications or with low mean Ages and Stages Questionnair scores at 6, 18, and 48-60 months after term.CONCLUSION: Chorionicity-specific intertwin birthweight discordance is a risk factor for induced preterm delivery and infant mortality, but not for lower scores for neurophysiological development at 6, 18, and 48-60 months. |
| Databáze: | OpenAIRE |
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