Does hormone therapy affect attention and memory in sleep-deprived women?
| Autor: | Paula Alhola, Nea Kalleinen, A Sofia Urrila, Mervi Kylmälä, M Karakorpi, Raija Portin, Päivi Polo-Kantola |
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| Rok vydání: | 2008 |
| Předmět: |
Adult
medicine.medical_specialty Hormone Replacement Therapy medicine.medical_treatment media_common.quotation_subject Audiology 050105 experimental psychology 03 medical and health sciences 0302 clinical medicine Memory Internal medicine Reaction Time Humans Medicine Attention 0501 psychology and cognitive sciences Effects of sleep deprivation on cognitive performance Episodic memory Aged media_common business.industry Working memory 05 social sciences Obstetrics and Gynecology Cognition General Medicine Middle Aged Cognitive test Postmenopause Sleep deprivation Endocrinology Sleep Deprivation Female Hormone therapy medicine.symptom Cognition Disorders business 030217 neurology & neurosurgery Vigilance (psychology) |
| Zdroj: | Climacteric. 11:221-232 |
| ISSN: | 1473-0804 1369-7137 |
| DOI: | 10.1080/13697130801958832 |
| Popis: | To evaluate whether hormone therapy (HT) modifies cognitive performance during sleep deprivation in postmenopausal women. Comparison was made with a group of young women.Participants included 26 postmenopausal women (age 58-72 years, 16 HT users, 10 non-users), 11 young women (age 20-26 years). They spent four consecutive nights in the sleep laboratory. Cognitive tests of attention, working memory, and verbal episodic memory were carried out after the baseline night, 25-h sleep deprivation, and recovery night.Sleep deprivation impaired performance in all groups. It was manifested either as delayed practice effect or deteriorated performance (p0.05). In simple reaction time and 10-choice reaction time, non-users and young maintained their performance, whereas HT users suffered a minor impairment (p0.01). In other measurements, there was no interaction of group and condition. In 10-choice reaction time and vigilance, postmenopausal women made fewer errors and omissions than the young (p0.05). For most tasks, all groups showed improvement after one recovery night.HT had a minor adverse effect on cognitive performance during sleep deprivation. Attention and memory deteriorated similarly in postmenopausal and young women, despite the lower initial performance level of postmenopausal women. One night of sleep ensured recovery in most tasks. |
| Databáze: | OpenAIRE |
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