Major hepatectomy is a safe modality for the treatment of intrahepatic cholangiocarcinoma in selected patients complicated with cirrhosis
| Autor: | Gang Liu, Hao Li, Bo Jiang, Ya-yong Li, Jin-shu Wu, Xin-tian Wang, Dao-jin Chen, Bu-ning Tian, Pin Lv |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
Liver Cirrhosis Male medicine.medical_specialty Cirrhosis Neoplasm Residual genetic structures Operative Time Blood Loss Surgical digestive system Gastroenterology Disease-Free Survival Cholangiocarcinoma Internal medicine Medicine Hepatectomy Humans In patient Hospital Mortality neoplasms Intrahepatic Cholangiocarcinoma Aged Retrospective Studies Aged 80 and over business.industry Perioperative Length of Stay medicine.disease digestive system diseases Survival Rate Bile Ducts Intrahepatic Bile Duct Neoplasms Surgery Female business Major hepatectomy |
| Zdroj: | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 18(1) |
| ISSN: | 1873-4626 |
| Popis: | The objective of this paper is to evaluate the perioperative outcomes of major hepatectomy for intrahepatic cholangiocarcinoma (ICC) in patients with cirrhosis.We retrospectively evaluated the preoperative, intraoperative, and postoperative findings in 42 consecutive patients with cirrhosis and in 102 patients with normal livers who underwent major hepatectomy for ICC.Preoperative liver function was worse in patients with cirrhosis compared to patients without cirrhosis. Cirrhotic patients had significantly higher intraoperative blood loss, longer operation time, and longer hospital stay than non-cirrhotic patients. However, the two groups had similar overall morbidity and hospital mortality rates and similar rates of liver failure or other complications. Their R0 resection rates, resection margin widths and disease-free survival rates were also similar.Major hepatectomy for ICC can be performed in selected cirrhotic patients with acceptable morbidity and mortality rates, as compared to patients without cirrhosis. |
| Databáze: | OpenAIRE |
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