CYTOPLASMIC INCLUSIONS AND VIRUS-LIKE PARTICLES IN BLAST CELLS IN ACUTE LYMPHOBLASTIC LEUKEMIA
| Autor: | Yoshimi Yamashita, Hiroyuki Tanaka, Shigeru Yano, Tokuhiro Ishihara, Masamitsu Inoue, Fumiya Uchino, Toshio Kaneko, Kenji Shinohara, Noboru Matsumoto, Mutsuo Takahashi |
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| Rok vydání: | 2008 |
| Předmět: |
Inclusion Bodies
Pathology medicine.medical_specialty Adolescent Cytoplasmic inclusion Lymphoblastic Leukemia General Medicine Vacuole Biology Virus Peripheral blood Leukemia Lymphoid Pathology and Forensic Medicine law.invention Microscopy Electron law Precursor cell Acute Disease Viruses medicine Humans Female Electron microscope Bacterial outer membrane |
| Zdroj: | Pathology International. 36:1231-1239 |
| ISSN: | 1320-5463 |
| DOI: | 10.1111/j.1440-1827.1986.tb02844.x |
| Popis: | Cytoplasmic inclusions and virus-like particles are described in blast cells of peripheral blood from a 16-year-old female with acute lymphoblastic leukemia. Three kinds of inclusions were identified on electron microscopy. The first type of inclusion was single membrane-bounded vacuoles, some of which contained virus-like particles, the second was lysosome-like structures, and the third appeared to be of mitochondrial origin. Virus-like particles were round in shape and had a diameter of 26 to 58 nm. They consisted of an electron-dense outer membrane and an electron-lucent core. At the present time the exact nature and significance of these virus-like particles still remain unclear. |
| Databáze: | OpenAIRE |
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