Symptomatic Spinal Epidural Lipomatosis with Severe Obesity at a Young Age
| Autor: | Hirotaka Haro, Nobuchika Kawasaki, Tetsuro Ohba, Shingo Maekawa, Toshiki Saito |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Epidural Space
Male medicine.medical_specialty medicine.medical_treatment Lipomatosis Neurogenic claudication Young Adult medicine Humans Orthopedics and Sports Medicine Young adult Urinary retention business.industry Laminectomy medicine.disease Middle age Epidural space Obesity Morbid Surgery Treatment Outcome medicine.anatomical_structure Adipose Tissue Sphincter Female Spinal Diseases medicine.symptom business |
| Zdroj: | Orthopedics. 34 |
| ISSN: | 1938-2367 0147-7447 |
| DOI: | 10.3928/01477447-20110427-25 |
| Popis: | Symptomatic spinal epidural lipomatosis is a rare disorder characterized by overgrowth of fat in the extradural space. Most patients have an underlying endocrine disorder, such as Cushing’s syndrome, or have taken exogenous steroids chronically. Although less common, obesity alone is thought to be a cause of spinal epidural lipomatosis, representing This article describes 2 unique cases of spinal epidural lipomatosis, both in young patients with underlying morbid obesity who presented with acute progressive leg weakness and urinary retention. The patients had no underlying endocrinopathy, nor any history of exogenous steroid use. They underwent emergency laminectomy and removal of epidural fat, and histopathological examination confirmed the diagnosis of epidural lipomatosis. Postoperatively, the patients demonstrated significant improvement. We conducted a review of the available English literature and compared the age distribution in each group. Based on our review, our 2 patients are considerably younger than those in past reports, especially in the patient group to which the steroid was not administered. In addition, few cases exist of spinal epidural lipomatosis with acute sphincter dysfunction and paraparesis. Our cases suggest that morbid obesity can lead to juvenile spinal epidural lipomatosis with acute neurological changes. |
| Databáze: | OpenAIRE |
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