Histochemical Study of Mast Cells from the Thymus of Mice Receiving ACTH1-24
Autor: | V. E. Sergeeva, E. M. Naumova |
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Rok vydání: | 2004 |
Předmět: |
Male
Serotonin medicine.medical_specialty Time Factors Cell Degranulation Mice Inbred Strains Thymus Gland General Biochemistry Genetics and Molecular Biology Mice Internal medicine medicine Animals Mast Cells Hormonal imbalance Heparin Histocytochemistry Chemistry Metachromasia Degranulation General Medicine Endocrinology Correlation analysis Cosyntropin Intracellular medicine.drug |
Zdroj: | Bulletin of Experimental Biology and Medicine. 138:93-96 |
ISSN: | 0007-4888 |
DOI: | 10.1023/b:bebm.0000046949.29614.09 |
Popis: | Synthetic ACTH1-24 analogue administered in a daily dose of 0.01 mg/kg decreased the number and size of mast cells and increased intracellular serotonin concentration. ACTH1-24 induced degranulation of young mast cells and release of undersulfated heparin. Correlation analysis showed that hormonal imbalance produced by ACTH1-24 was accompanied by redistribution of bioamines. |
Databáze: | OpenAIRE |
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