The Combined Pharmacological Stress Echocardiography Protocol for Predicting Improvement of Global Left Ventricular Systolic Function After Revascularisation
| Autor: | Zainab Abdel-Salam, Wail Nammas |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine medicine.medical_specialty Cardiotonic Agents Time Factors Systole Vasodilator Agents Systolic function Pharmacological stress Sensitivity and Specificity Ventricular Function Left Ventricular Dysfunction Left Predictive Value of Tests Dobutamine Internal medicine Occlusion medicine Stress Echocardiography Health Status Indicators Humans Prospective Studies Myocardial infarction Angioplasty Balloon Coronary Coronary Artery Bypass Protocol (science) business.industry Coronary Stenosis Dipyridamole Middle Aged Prognosis medicine.disease medicine.anatomical_structure Cardiology Female Cardiology and Cardiovascular Medicine business Echocardiography Stress medicine.drug Artery |
| Zdroj: | Heart, Lung and Circulation. 19:81-89 |
| ISSN: | 1443-9506 |
| DOI: | 10.1016/j.hlc.2009.08.008 |
| Popis: | Background We compared the prognostic power of three pharmacological stress echocardiography protocols for predicting improvement of global left ventricular systolic function following revascularisation. Methods We enrolled 100 consecutive patients with significant coronary stenosis/occlusion and regional dys-synergy in the affected artery territory. Patients underwent assessment of regional and global left ventricular systolic function. They underwent then three pharmacological stress echocardiography protocols: low dose dobutamine, infra-low dose dipyridamole, combined protocol. All patients underwent coronary revascularisation. Echocardiography was repeated 8 weeks later. Predicted function improvement by the three protocols was compared with actual improvement. Results The combined protocol was more sensitive to predict systolic function improvement after revascularisation, but less specific, the diagnostic accuracy was similar among the three protocols. A cutoff value of 6 viable segments best predicted global function improvement with the combined protocol. Conclusions The combined protocol has a higher sensitivity but lower specificity to predict global left ventricular systolic function improvement after revascularisation, as compared to the other two protocols. |
| Databáze: | OpenAIRE |
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