Feasibility of a Hospital-at-Home program for Autologous Hematopoietic Stem Cell Transplantation

Autor: Soledad González-Barrera, Guillermo Martín-Sánchez, Juan José Parra-Jordán, Sara Fernández-Luis, José A. Calvo, Rocío Lobeira, Lucrecia Yañez, Asunción Manzano, Carolina Carrera, Julio Baro, Carlos Richard, Arancha Bermúdez, Enrique M. Ocio, Pedro Sanroma
Rok vydání: 2022
Předmět:
Zdroj: Transplantation and cellular therapy.
ISSN: 2666-6367
Popis: The Hospital at Home (HaH) model has been positioned as an appropriate therapeutic strategy for selected patients undergoing an autologous hematopoietic stem cell transplantation (ASCT). This care model provides hospital equivalent care, both in quality and quantity, with medical and nursing staff that go to the patient's home. We describe our experience with a full at home model for patients undergoing ASCT during the phase of aplasia.Patients who met the eligibility criteria between January 1997 and December 2019, were discharged from the hospital and admitted into the HaH-ASCT program on the same day they in which hematopoietic stem cells were infused.84 patients were included. The median age was 54 [16-74]. The median duration of admission in the HaH program was 17 [3-86] days. Only 10 of these patients (12%) required hospital re-admission in the hematology department, 9 of them due to sepsis and one because of family care support claudication. 72 patients (86%) had a neutropenic fever episode during the HAH admission with a median duration of 2 [1-11] days. Empiric intravenous antimicrobial therapy was prescribed in all of them. Most patients (88%) presented with mucositis (44% grade 3-4). Parenteral nutrition was administered in 26% of patients for a median of 6 [1-12] days. 94% of patients required at least one blood product transfusion at home. There was no transplant related mortality during the HaH-ASCT program or in the patients readmitted.With a careful selection of patients and a comprehensive and well experienced multidisciplinary team (doctors, nurses, auxiliary nurses) in the HaH department and in close collaboration with the hematology department, allows a complete at home management of ASCT patients immediately after the HSC infusion. This allows patients undergoing an aggressive procedure such as ASCT to remain in their own familiar environment providing a better quality of life, with a program that has demonstrated to be effective and safe, with a low incidence of complications and with no associated mortality.
Databáze: OpenAIRE