Studies on memory: inhibitors of protein synthesis also inhibit catecholamine synthesis
| Autor: | Louis B. Flexner, Richard H. Goodman |
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| Rok vydání: | 1975 |
| Předmět: |
Male
medicine.medical_specialty Pyrrolidines Dopamine Nerve Tissue Proteins Endogeny Cycloheximide Biology Mice Norepinephrine chemistry.chemical_compound Catecholamines Memory Internal medicine medicine Protein biosynthesis Animals Anisomycin Multidisciplinary Brain Endocrinology chemistry Puromycin Catecholamine Research Article medicine.drug |
| Zdroj: | Proceedings of the National Academy of Sciences. 72:4660-4663 |
| ISSN: | 1091-6490 0027-8424 |
| DOI: | 10.1073/pnas.72.11.4660 |
| Popis: | The rates of accumulation of newly synthesized catecholamines and endogenous catecholamine levels in mice were determined after treatment with cycloheximide, acetoxycycloheximde, puromycin, and anisomycin. The rates of accumulation were found to be decreased by all antibiotics tested, weakening the assumption that their amnestic effects are due solely to inhibition of protein synthesis. |
| Databáze: | OpenAIRE |
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