Ultrasound triggered image-guided drug delivery
| Autor: | Christopher S. Hall, Oliver C. Steinbach, Klaus Tiemann, Holger Gruell, Alexander L. Klibanov, Marcel Rene Bohmer |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Drug
medicine.medical_specialty Drug Carriers business.industry media_common.quotation_subject Ultrasound General Medicine Equipment Design Sonication Drug Delivery Systems Drug delivery Pressure sensitive Microbubbles Medicine Radiology Nuclear Medicine and imaging Temperature sensitive Medical physics Image guidance Drug carrier business Nuclear medicine media_common Ultrasonography |
| Zdroj: | European journal of radiology. 70(2) |
| ISSN: | 1872-7727 |
| Popis: | The integration of therapeutic interventions with diagnostic imaging has been recognized as one of the next technological developments that will have a major impact on medical treatments. Important advances in this field are based on a combination of progress in guiding and monitoring ultrasound energy, novel drug classes becoming available, the development of smart delivery vehicles, and more in depth understanding of the mechanisms of the cellular and molecular basis of diseases. Recent research demonstrates that both pressure sensitive and temperature sensitive delivery systems hold promise for local treatment. The use of ultrasound for the delivery of drugs has been demonstrated in particular the field of cardiology and oncology for a variety of therapeutics ranging from small drug molecules to biologics and nucleic acids. |
| Databáze: | OpenAIRE |
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