Effect of β-adrenergic blocking agents on mortality rate in patients not revascularized after myocardial infarction: Data from a large HMO
| Autor: | Robert J. Lundstrom, Hal V. Barron, Sami Viskin, Candice C. Wong, Joe V. Selby, Bix E. Swain, Alison Truman |
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| Rok vydání: | 1997 |
| Předmět: |
Male
Risk Coronary angiography medicine.medical_specialty medicine.medical_treatment Adrenergic beta-Antagonists Myocardial Infarction Revascularization Internal medicine Odds Ratio medicine Humans In patient Myocardial infarction Aged Retrospective Studies business.industry Mortality rate Health Maintenance Organizations β adrenergic Middle Aged medicine.disease Treatment Outcome Relative risk Cardiology Female San Francisco Cardiology and Cardiovascular Medicine business |
| Zdroj: | American Heart Journal. 134:608-613 |
| ISSN: | 0002-8703 |
| DOI: | 10.1016/s0002-8703(97)70042-5 |
| Popis: | We investigated whether patients who do not undergo coronary angiography and therefore any form of revascularization after a myocardial infarction derive greater benefit from chronic beta-blocker therapy than patients who undergo coronary angiography. With multivariate analyses, treatment with beta-blockers was a much stronger predictor of survival in patients who did not undergo coronary angiography (relative risk = 0.38, p = 0.005) than in those patients who did undergo catheterization (p0.05 for interaction). Our findings provide direct support for the recommendation by the American College of Cardiology/American Heart Association task force that beta-blocker therapy should be initiated for all infarct survivors who do not undergo revascularization and who have no contraindications. |
| Databáze: | OpenAIRE |
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