Presence of Magnetic Resonance Imaging-Defined Inflammation Particularly in Overweight and Obese Women Increases Risk of Radiographic Knee Osteoarthritis: The POMA Study

Autor: Frank W. Roemer, Ali Guermazi, Patrick Omoumi, T. Fujii, C. Kent Kwoh, Michael J. Hannon, David J. Hunter, Felix Eckstein
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Male
medicine.medical_specialty
Knee Joint
Radiography
Osteoarthritis
Overweight
Odds
03 medical and health sciences
0302 clinical medicine
Polymethacrylic Acids
Rheumatology
Internal medicine
Synovitis
medicine
Humans
Obesity
Female
Inflammation/complications
Knee Joint/diagnostic imaging
Knee Joint/pathology
Magnetic Resonance Imaging
Obesity/complications
Obesity/diagnostic imaging
Obesity/epidemiology
Osteoarthritis
Knee/diagnostic imaging
Osteoarthritis
Knee/epidemiology
Osteoarthritis
Knee/etiology
Overweight/complications
Overweight/diagnostic imaging
Overweight/epidemiology
Synovitis/complications
Synovitis/diagnostic imaging
Synovitis/epidemiology
Inflammation
030203 arthritis & rheumatology
medicine.diagnostic_test
business.industry
Magnetic resonance imaging
Osteoarthritis
Knee
medicine.disease
medicine.symptom
business
Body mass index
Zdroj: Arthritis care & research, vol. 74, no. 8, pp. 1391-1398
Popis: The present study was undertaken to assess whether the odds for incident radiographic osteoarthritis (OA) differ between men and women in regard to body mass index (BMI) and inflammatory magnetic resonance imaging (MRI) markers 1 and 2 years prior, and whether the presence of inflammation on MRI differs between normal-weight and overweight/obese individuals who develop radiographic OA up to 4 years prior. We studied 355 knees from the Osteoarthritis Initiative study that developed incident radiographic OA and 355 matched controls. MRIs were read for effusion-synovitis and Hoffa-synovitis for up to 4 consecutive annual time points. Subjects were classified as normal-weight (BMI
Databáze: OpenAIRE
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