| Autor: |
Kahlert, Christian R, Strahm, Carol, Güsewell, Sabine, Cusini, Alexia, Brucher, Angela, Goppel, Stephan, Möller, Elisabeth, Möller, J Carsten, Ortner, Manuela, Ruetti, Markus, Stocker, Reto, Vuichard-Gysin, Danielle, Besold, Ulrike, McGeer, Allison, Risch, Lorenz, Friedl, Andrée, Schlegel, Matthias, Vernazza, Pietro, Kuster, Stefan P, Kohler, Philipp |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Kahlert, Christian R; Strahm, Carol; Güsewell, Sabine; Cusini, Alexia; Brucher, Angela; Goppel, Stephan; Möller, Elisabeth; Möller, J Carsten; Ortner, Manuela; Ruetti, Markus; Stocker, Reto; Vuichard-Gysin, Danielle; Besold, Ulrike; McGeer, Allison; Risch, Lorenz; Friedl, Andrée; Schlegel, Matthias; Vernazza, Pietro; Kuster, Stefan P and Kohler, Philipp (2023). Post-acute sequelae after SARS-CoV-2 infection by viral variant and vaccination status: a multicenter cross-sectional study. (In Press). Clinical infectious diseases Oxford University Press 10.1093/cid/ciad143 |
| DOI: |
10.48350/179910 |
| Popis: |
BACKGROUND Disentangling the effects of SARS-CoV-2 variants and vaccination on the occurrence of post-acute sequelae of SARS-CoV-2 (PASC) is crucial to estimate and reduce the burden of PASC. METHODS We performed a cross-sectional analysis (May/June 2022) within a prospective multicenter healthcare worker (HCW) cohort in North-Eastern Switzerland. HCW were stratified by viral variant and vaccination status at time of their first positive SARS-CoV-2 nasopharyngeal swab. HCW without positive swab and with negative serology served as controls. The sum of eighteen self-reported PASC symptoms was modeled with univariable and multivariable negative-binomial regression to analyse the association of mean symptom number with viral variant and vaccination status. RESULTS Among 2'912 participants (median age 44 years, 81.3% female), PASC symptoms were significantly more frequent after wild-type infection (estimated mean symptom number 1.12, p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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