Differential Expression of Hox and Notch Genes in Larval and Adult Stages of Echinococcus granulosus
| Autor: | Ebrahim Saedi Dezaki, Bruno Gottstein, Pooya Ghasemi Nejad Almani, Farideh Tohidi, Majid Fasihi Harandi, Mohammad Yaghoobi, Elham Taheri |
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| Rok vydání: | 2016 |
| Předmět: |
Male
0301 basic medicine 610 Medicine & health 03 medical and health sciences Dogs parasitic diseases Animals Humans Parasite hosting Juvenile Differential expression Echinococcus granulosus Hox gene HoxB7 gene Gene Homeodomain Proteins Larva Sheep Receptors Notch 630 Agriculture biology Gene Expression Profiling Gene Expression Regulation Developmental biology.organism_classification Cell biology cystic echinococcosis 030104 developmental biology Infectious Diseases Real-time polymerase chain reaction notch gene Immunology Original Article Parasitology real-time PCR |
| Zdroj: | Dezaki, Ebrahim Saedi; Yaghoobi, Mohammad Mehdi; Taheri, Elham; Almani, Pooya Ghaseminejad; Tohidi, Farideh; Gottstein, Bruno; Harandi, Majid Fasihi (2016). Differential Expression of Hox and Notch Genes in Larval and Adult Stages of Echinococcus granulosus. Korean journal of parasitology, 54(5), pp. 653-658. Korean Society for Parasitology and Tropical Medicine 10.3347/kjp.2016.54.5.653 The Korean Journal of Parasitology |
| ISSN: | 1738-0006 0023-4001 |
| DOI: | 10.3347/kjp.2016.54.5.653 |
| Popis: | This investigation aimed to evaluate the differential expression of HoxB7 and notch genes in different developmental stages of Echinococcus granulosus sensu stricto. The expression of HoxB7 gene was observed at all developmental stages. Nevertheless, significant fold differences in the expression level was documented in the juvenile worm with 3 or more proglottids, the germinal layer from infected sheep, and the adult worm from an experimentally infected dog. The notch gene was expressed at all developmental stages of E. granulosus; however, the fold difference was significantly increased at the microcysts in monophasic culture medium and the germinal layer of infected sheep in comparison with other stages. The findings demonstrated that the 2 aforementioned genes evaluated in the present study were differentially expressed at different developmental stages of the parasite and may contribute to some important biological processes of E. granulosus. |
| Databáze: | OpenAIRE |
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