High prevalence of carotid artery disease in patients with atheromatous renal artery stenosis

Autor: Anna-Maria Belli, M B Papavassiliou, K Khaw, T.M. Buckenham, T Hall, C. G. Missouris, Graham A. MacGregor
Rok vydání: 1998
Předmět:
Zdroj: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 13(4)
ISSN: 0931-0509
Popis: Background. Renovascular disease is the most frequently encountered secondary cause of hypertension and is one of the few potentially reversible causes of Introduction chronic renal failure. These patients are at increased risk of having cerebrovascular events following operative management for atheromatous renal-artery sten- Renovascular disease is the most frequently encounosis. We studied the prevalence of carotid-artery disease tered secondary cause of hypertension and is one of in patients with atheromatous renal-artery stenosis. the few potentially reversible causes of chronic renal Methods. A cross-sectional study was carried out on failure [1,2]. It is also an important and potentially 38 consecutive patients with atheromatous renal-artery reversible cause of recurrent pulmonary oedema and stenosis who underwent renal-artery balloon angiopla- apparent congestive heart failure in patients without sty. Extracranial carotid atherosclerosis was assessed overt coronary or valvular heart disease [3‐5]. Certain using a commercially available colour Doppler scanner, groups of patients, those with peripheral vascular depending on the velocity of the peak systolic wave- disease, are particularly at risk of having renal-artery form in the internal carotid artery, and the internal disease [6‐8]. In these patients the prevalence of athercarotid-artery/common carotid-artery ratio. omatous renal-artery stenosis increases with increasing Results. Twenty-one patients (55.3%) had normal or severity of peripheral vascular disease [6 ]. However, mild carotid-artery disease, 10 (26.3%) had moderate, little is known of the prevalence and importance of and 7 (18.4%) had severe carotid-artery disease. Nine coexistent carotid-artery disease in patients with patients had previously suVered a stroke (eight infarc- atheromatous renal-artery stenosis. tion, one haemorrhage) and one had multiple transient We performed a cross-sectional study to investigate ischaemic attacks. the prevalence, severity, and vascular risk factors of Conclusions. Our results suggest that, in patients with carotid-artery disease in patients undergoing elective atheromatous renal-artery disease severe enough to renal percutaneous balloon angioplasty. require angioplasty, 4 out of 10 appear to have moderate to severe carotid-artery disease. This may explain Subjects and methods the increased prevalence of atherothrombotic cerebrovascular events in these patients, and also previous observations that, following operative management for We studied 38 hypertensive subjects (mean age 65.5±7.9 years; 21 males) who were consecutively referred between
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