Detection of ventricular premature beats based on the pressure signals of a hemodialysis machine
Autor: | Juan Pablo Martinez, Mattias Holmer, Leif Sörnmo, Frida Sandberg, Eduardo Gil, Bo Olde |
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Rok vydání: | 2017 |
Předmět: |
medicine.medical_specialty
medicine.medical_treatment 0206 medical engineering Biomedical Engineering Biophysics Blood Pressure 02 engineering and technology 030204 cardiovascular system & hematology Signal 03 medical and health sciences 0302 clinical medicine Electrolyte imbalance Renal Dialysis Internal medicine medicine Humans Pulse (signal processing) Venous pressure business.industry Signal Processing Computer-Assisted medicine.disease Linear discriminant analysis 020601 biomedical engineering Ventricular Premature Complexes Pulse pressure cardiovascular system Cardiology Ventricular premature beats Hemodialysis business |
Zdroj: | Medical engineeringphysics. 51 |
ISSN: | 1873-4030 |
Popis: | Monitoring of ventricular premature beats (VPBs), being abundant in hemodialysis patients, can provide information on cardiovascular instability and electrolyte imbalance. In this paper, we describe a method for VPB detection which explores the signals acquired from the arterial and the venous pressure sensors, located in the extracorporeal blood circuit of a hemodialysis machine. The pressure signals are mainly composed of a pump component and a cardiac component. The cardiac component, severely overshadowed by the pump component, is estimated from the pressure signals using an earlier described iterative method. A set of simple features is extracted, and linear discriminant analysis is performed to classify beats as either normal or ventricular premature. Performance is evaluated on signals from nine hemodialysis treatments, using leave-one-out crossvalidation. The simultaneously recorded and annotated photoplethysmographic signal serves as the reference signal, with a total of 149,686 normal beats and 3574 VPBs. The results show that VPBs can be reliably detected, quantified by a Youden's J statistic of 0.9, for average cardiac pulse pressures exceeding 1 mmHg; for lower pressures, the J statistic drops to 0.55. It is concluded that the cardiac pressure signal is suitable for VPB detection, provided that the average cardiac pulse pressure exceeds 1 mmHg. |
Databáze: | OpenAIRE |
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