Perioperative SARS-CoV-2 infection is not associated with increased morbidity and mortality rates after pancreatico-duodenectomy. a single center experience
| Autor: | I. Danciuc, Dana Tomescu, Vladislav Brasoveanu, A. Tudor, I. Popescu, Traian Dumitrascu, Simona Dima, Nicolae Bacalbasa, Florin Botea, M. Olita, C. David, R. Zamfir |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Hepatology Gastric emptying business.industry Talking Poster 16 - Pancreas Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Mortality rate Gastroenterology Perioperative Single Center Intensive care unit law.invention Duodenectomy law Internal medicine Medicine business Pathological |
| Zdroj: | HPB : The Official Journal of the International Hepato Pancreato Biliary Association |
| ISSN: | 1477-2574 1365-182X |
| Popis: | Introduction: SARS-CoV-2 infection represented a huge burden on the healthcare systems worldwide during the pandemic year 2020. Perioperative infection with SARS-CoV-2 was previously associated with increased mortality and morbidity rates for few surgical procedures, but data about pancreatic resections are scarce. The study aims to assess the impact of perioperative SARS-CoV-2 infection on early outcomes after pancreatico-duodenectomies. Methods: The data of 50 patients with pancreatico-duodenectomies performed during the pandemic year 2020 at our institution were retrospectively assessed from a prospective electronic database. The patients were divided into two groups: with and without perioperative SARS-CoV-2 infection. Demographic, clinical, bioumoral, pathological, intraoperative and early postoperative outcomes were compared between the groups, with the appropriate statistical tests. All patients were negative for SARS-CoV-2 infection at RT-PCR test 48 hours prior to surgery. Results: A number of 8 patients (16%) were diagnosed with SARS-CoV-2 infection at a median POD 11 (range, 6 – 32 POD). Perioperative SARS-CoV-2 infection was only associated with statistically significant increased overall length of hospital stays (33 vs. 15 days, p < 0.0001) but not with increased intensive care unit stay, overall or severe morbidity, clinically relevant pancreatic fistulae, delayed gastric emptying, hemorrhage, bile leak, pulmonary complications or in-hospital mortality rates (p values ≥ 0.062, ns). Conclusion: Perioperative SARS-CoV-2 infection was not associated with increased morbidity or mortality rates after pancreatico-duodenectomies. However, significant prolonged overall hospital stays were observed. The data should be interpreted with caution due to the limited number of patients. |
| Databáze: | OpenAIRE |
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