Percutaneous treatments of primary aneurysmal bone cysts: systematic review and meta-analysis
| Autor: | Matheus Ricardo Kishimoto Teixeira, Juan Pablo Aitken Saavedra, Rafael Giorgis, Carlos Enrique Cuevas-Suárez, Francisco Wilker Mustafa Gomes Muniz, Gabriel Schmitt Cruz |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Percutaneous medicine.medical_treatment 03 medical and health sciences 0302 clinical medicine Sclerotherapy medicine Humans Orthopedics and Sports Medicine 030212 general & internal medicine Embolization Sclerotherapies 030222 orthopedics business.industry Arterial Embolization Embolization Therapeutic Surgery Clinical trial Bone Cysts Aneurysmal Treatment Outcome Meta-analysis Observational study Neoplasm Recurrence Local business |
| Zdroj: | European journal of orthopaedic surgerytraumatology : orthopedie traumatologie. 31(7) |
| ISSN: | 1432-1068 |
| Popis: | To systematically review the literature to determine recurrence rates of percutaneous treatments for primary aneurysmal bone cysts (ABC). Search strategies were performed in the following databases: PubMed, SCIELO, LILACS and BVS, using terms in English, Spanish and Portuguese (PROSPERO Registration Number: CRD42020170340). Longitudinal studies, either observational or clinical trials, with at least five patients and with a mean of 18 months of follow-up were included. Studies had to use any type of percutaneous treatments and report the recurrence rates of primary ABC treatment. Studies selection, data extraction and risk of bias assessment were performed independently by two researchers. A global meta-analysis was carried out to assess the proportion of recurrence. Studies were categorized into two subgroups: selective arterial embolization and sclerotherapy. Thirteen studies were included in the present study. The average success rate of percutaneous treatments for ABC was 91.11%, with a total of 37 lesions recurrences in the 416 patients. The sex ratio was 1:1. The subgroup of sclerotherapies presented a lower proportion of recurrence. The proportion of recurrence in the subgroup of selective arterial embolization was 19% (95%IC 12.11–27.54) and that of sclerotherapies was 6% (95%IC 3.65–9.19). Both percutaneous treatments for ABC are effective, showing a lower rate of recurrence. Sclerotherapy treatments seem to be promising, but further clinical trials must be conducted with a longer follow-up. |
| Databáze: | OpenAIRE |
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