Airways narrowing in exercise in normal subjects and the effect of disodium cromoglycate
| Autor: | N.M. Lefcoe, Dildar Ahmad, N.A.M. Paterson |
|---|---|
| Rok vydání: | 1973 |
| Předmět: |
Pulmonary and Respiratory Medicine
Adult Male Inhalation Chest disease business.industry Physical Exertion Smoking Vital Capacity Bronchi medicine.disease Rhonchi Constriction respiratory tract diseases Atopy Airway Obstruction Spirometry Anesthesia Disodium cromoglycate Cromolyn Sodium medicine Methods Humans medicine.symptom business |
| Zdroj: | British journal of diseases of the chest. 67(3) |
| ISSN: | 0007-0971 |
| Popis: | In a group of 26 young healthy adults, with no history of chest disease or atopy, post-exercise airways narrowing was demonstrated in both smokers and non-smokers. Inhalation of disodium cromoglycate (DSCG) on 5 occasions over 24 hours significantly reduced the post-exercise airways narrowing. The reduction was greater in the non-smokers, to the extent that post-exercise ventilatory tests showed no decline in DSCG-treated non-smokers. Sixteen subjects exhibited post-exercise rhonchi. After DSCG inhalation, post-exercise rhonchi were heard in only 8 subjects. The maximum mid-expiratory flow rate (MMEF) appeared to be a more sensitive measure of post-exercise change than either the forced expiratory volume 1st second (FEV 1 ) or the specific airways conductance (SG aw ). |
| Databáze: | OpenAIRE |
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