Five polyketides isolated from the marine-derived fungus Arthrinium Sp
| Autor: | Dao-Qiong Zheng, Jinzhong Xu, Wanjing Ding, Zhaihai Zhao, Pin-Mei Wang |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
biology
010405 organic chemistry Chemistry Stereochemistry Organic Chemistry Arthrinium Plant Science Fungus Arthrinium sp biology.organism_classification 01 natural sciences Biochemistry 0104 chemical sciences Analytical Chemistry 010404 medicinal & biomolecular chemistry Polyketide Cell culture Cytotoxicity |
| DOI: | 10.6084/m9.figshare.10029164 |
| Popis: | Four new polyketides including two arthrinic acid derivatives (1–2), one phenolic derivative (3) and (S)-3-hydroxy-6-(2-hydroxypropyl)-5-methyl-2H-pyran-2-one (4) along with one methyl ester of arthrinic acid (5) were isolated from the culture broth of Arthrinium sp., which was an entophytic fungus of clam worm. Their structures were identified on the basis of HR-ESI-MS and NMR spectral analyses together with advanced Mosher's method. In the assay of inhibiting the prostate cancer PC3 cell line, none of the isolated compounds showed significant cytotoxicity. |
| Databáze: | OpenAIRE |
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