Elastic tissue changes in skin following PUVA therapy

Autor: J. H. Mottaz, S.A. Muller, Brian D. Zelickson, Alvin S. Zelickson
Rok vydání: 1980
Předmět:
Zdroj: Journal of the American Academy of Dermatology. 3:186-192
ISSN: 0190-9622
DOI: 10.1016/s0190-9622(80)80258-1
Popis: Treatment of psoriasis with psoralens and high-intensity long-wave ultraviolet light (PUVA) produces changes in the ultrastructure of elastic tissue in skin. Early alterations consist of a loss of elastin followed by a breakdown of the microfibrils and subsequent fragmentation of the elastic fiber. Tissue examined 15 months after treatment was stopped still showed marked ultrastructural changes in the elastic fibers.
Databáze: OpenAIRE