Increased prevalence of antibiotic-resistant E. coli in gulls sampled in Southcentral Alaska is associated with urban environments

Autor:	Josef D. Järhult, Jonas Bonnedahl, Stefan Börjesson, Andrew M. Ramey, Gabriel Gustafsson Hall, Clara Atterby
Přispěvatelé:	Brianna Williams, Morgan Walker, Jenny Isaksson, Badrul Hasan, Henrik Reutherborg, Christina Ahlström, John Pearce, John Reed, Scott Hatch, U.S. Geological Survey
Jazyk:	angličtina
Rok vydání:	2016
Předmět:	0301 basic medicine Veterinary medicine Infectious Medicine Epidemiology medicine.drug_class 030106 microbiology Antibiotics Wildlife Infektionsmedicin Environmental Science (miscellaneous) medicine.disease_cause anthropogenic lcsh:Infectious and parasitic diseases 03 medical and health sciences pAmpC Antibiotic resistance medicine lcsh:RC109-216 Original Research Article antimicrobial resistance Escherichia coli Feces Larus glaucescens biology Ecology biology.organism_classification 030104 developmental biology ESBL gull Alaska antibiotic resistance gulls wildlife Larus Bacteria
Zdroj:	Infection Ecology & Epidemiology, Vol 6, Iss 0, Pp 1-7 (2016) Infection Ecology & Epidemiology Infection Ecology & Epidemiology; Vol 6 (2016)
ISSN:	2000-8686
Popis:	Background : Antibiotic-resistant bacteria pose challenges to healthcare delivery systems globally; however, limited information is available regarding the prevalence and spread of such bacteria in the environment. The aim of this study was to compare the prevalence of antibiotic-resistant bacteria in large-bodied gulls ( Larus spp.) at urban and remote locations in Southcentral Alaska to gain inference into the association between antibiotic resistance in wildlife and anthropogenically influenced habitats. Methods : Escherichia coli was cultured ( n =115 isolates) from fecal samples of gulls (n=160) collected from a remote location, Middleton Island, and a more urban setting on the Kenai Peninsula. Results : Screening of E. coli from fecal samples collected from glaucous-winged gulls ( Larus glaucescens ) at Middleton Island revealed 8% of isolates were resistant to one or more antibiotics and 2% of the isolates were resistant to three or more antibiotics. In contrast, 55% of E. coli isolates derived from fecal samples collected from large-bodied gulls (i.e. glaucous, herring [ Larus argentatus ], and potentially hybrid gulls) on the Kenai Peninsula were resistant to one or more antibiotics and 22% were resistant to three or more antibiotics. In addition, total of 16% of the gull samples from locations on the Kenai Peninsula harbored extended-spectrum cephalosporin-resistant E. coli isolates (extended-spectrum beta-lactamases [ESBL] and plasmid-encoded AmpC [pAmpC]), in contrast to Middleton Island where no ESBL- or pAmpC-producing isolates were detected. Conclusion : Our findings indicate that increased prevalence of antibiotic resistance is associated with urban environments in Southcentral Alaska and presumably influenced by anthropogenic impacts. Further investigation is warranted to assess how migratory birds may maintain and spread antimicrobial-resistant bacteria of relevance to human and animal health. Keywords: ESBL; pAmpC; antimicrobial resistance; anthropogenic; gull (Published: 19 September 2016) Citation: Infection Ecology and Epidemiology 2016, 6: 32334 - http://dx.doi.org/10.3402/iee.v6.32334
Databáze:	OpenAIRE
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