Popis: |
Figure S2. Reference tree used as a backbone for defining hemagglutinin (HA) H3 subtype clades. The defined H3 clades are Cluster I (purple), Cluster II (lilac), Cluster III (navy), Cluster IV(red), Cluster IVA (orange), Cluster IVB (mustard), Cluster IVC (light green), Cluster IVD (dark green), Cluster IVE (seafoam), Cluster IVF (blue), human-like (magenta). Human seasonal (black). The reference tree was built using FastTree2 v2.1.9 [32] to infer the best-known maximum-likelihood tree implementing a general time reversible model of nucleotide substitution with a CAT model of rate heterogeneity with branch lengths rescaled to optimize the Gamma20 likelihood. (PDF 7 kb) |