Aloe vera gel and thyroid hormone cream may improve wound healing in Wistar rats
| Autor: | Saeed Zarein-Dolab, Jaleh Mohsenifar, Masoomeh Dadpay, Roohollah Gazor, Mahsa Tarameshloo, Mohsen Norouzian |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
medicine.medical_specialty
Histology Thyroid hormones Wound healing Pharmacology Silver sulfadiazine Aloe vera Cellular and Molecular Neuroscience Dermis medicine Aloe biology business.industry Cell Biology & Microscopical Research Thyroid Therapeutic effect Cell Biology biology.organism_classification Surgery Wistar rats medicine.anatomical_structure Original Article Anatomy business Developmental Biology medicine.drug Hormone Blood vessel |
| Zdroj: | Anatomy & Cell Biology |
| ISSN: | 2093-3673 2093-3665 |
| DOI: | 10.5115/acb.2012.45.3.170 |
| Popis: | Therapeutic effects of various treatment options in wound healing have been one of the most controversial issues in surgical science. The present study was carried out to examine and compare the effects of Aloe vera gel, thyroid hormone cream and silver sulfadiazine cream onsutured incisions in Wistar rats. In a randomized controlled trial, thirty-six Wistar male rats, 250 to 300 g, received surgical incisions followed by topical application of Aloe vera gel, thyroid hormone cream and silver sulfadiazine 1%. To assess the efficacy of each treatment technique, a histological approach was used to evaluate the mean number of fibroblasts, macrophages, neutrophils, blood vessel sections and thickness of the regenerating epithelium and dermis on days 4, 7 and 14. Re-epithelialization and angiogenesis were significantly improved in Aloe vera gel group compared with the other treatments while thyroid hormone cream had positive effects on day 4 (P≤0.05). Topical administration of Aloe vera gel is recommended as the treatment of choice for surgical incisions. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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