Where and when to vaccinate? Interdisciplinary design and evaluation of the 2018 Tanzanian anti-rabies campaign
| Autor: | Margaret M. Fasina, Japhet Killewo, Raphael Sallu, Selemani Makungu, Justine K. Assenga, Mohamed Hussein, Edward G. Otieno, Martin Ruheta, Justus Ochieng, Bachana Rubegwa, Robinson H. Mdegela, Walter Marandu, Hezron E. Nonga, James Warioba, Fred Kafeero, Violet M. Kessy, Niwael Mtui-Malamsha, Almira L. Hoogesteijn, Athumani M. Lupindu, Gundelinda Francis, Emmanuel Swai, Moses Ole-Neselle, Pius Masanja, Eliona Kaaya, Jubilate Bernard, Erick V.G. Komba, Janique Savy, Folorunso Oludayo Fasina, Hija Choyo, Gladys Reuben Mahiti, Yilma J. Makonnen, Ariel L. Rivas |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Rabies Cost-Benefit Analysis 030106 microbiology Psychological intervention Geo-epidemiology Cat Diseases Tanzania lcsh:Infectious and parasitic diseases 03 medical and health sciences Dogs 0302 clinical medicine Dog medicine Animals Humans lcsh:RC109-216 Dog Diseases 030212 general & internal medicine Socioeconomics One health Health economics biology Immunization Programs Vaccination Human health General Medicine biology.organism_classification medicine.disease Infectious Diseases Geography One Health Rabies Vaccines Interdisciplinary design Cats Female Rural area |
| Zdroj: | International Journal of Infectious Diseases, Vol 95, Iss, Pp 352-360 (2020) |
| ISSN: | 1201-9712 |
| Popis: | Objectives Hoping to improve health-related effectiveness, a two-phase vaccination against rabies was designed and executed in northern Tanzania in 2018, which included geo-epidemiological and economic perspectives. Methods Considering the local bio-geography and attempting to rapidly establish a protective ring around a city at risk, the first phase intervened on sites surrounding that city, where the population density was lower than in the city at risk. The second phase vaccinated a rural area. Results No rabies-related case has been reported in the vaccinated areas for over a year post-immunisation; hence, the campaign is viewed as highly cost-effective. Other metrics included: rapid implementation (concluded in half the time spent on other campaigns) and the estimated cost per protected life, which was 3.28 times lower than in similar vaccinations. Conclusions The adopted design emphasised local bio-geographical dynamics: it prevented the occurrence of an epidemic in a city with a higher demographic density than its surrounding area and it also achieved greater effectiveness than average interventions. These interdisciplinary, policy-oriented experiences have broad and immediate applications in settings of limited and/or time-sensitive (expertise, personnel, and time available to intervene) resources and conditions. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|