The Immunogenicity of Fractional Intradermal Doses of the Inactivated Poliovirus Vaccine Is Associated With the Size of the Intradermal Fluid Bleb

Autor:	David Jeffries, Ngozi Moneke-Anyanwoke, Mariama Badjie Hydara, Ed Clarke, Ama Umesi, Ananda S Bandyopadhyay, Michael Royals, Courtney Jarrahian, Abdul Khalie Muhammad, Jane U. Adetifa, Adedapo O Bashorun, Jack Bibby, Michael Okoye, Beate Kampmann, Sarah Mulwa, Yauba Saidu, Elishia Roberts, Ralf Clemens, Ikechukwu Adigweme
Jazyk:	angličtina
Rok vydání:	2017
Předmět:	Microbiology (medical) genetic structures Injections Intradermal inactivated poliovirus vaccine Immunology polio 030231 tropical medicine Antibodies Viral Microbiology 03 medical and health sciences Blister 0302 clinical medicine Seroepidemiologic Studies Humans Medicine 030212 general & internal medicine Bleb (cell biology) intradermal Science & Technology business.industry Immunogenicity Infant 11 Medical And Health Sciences 06 Biological Sciences Virology eye diseases Poliovirus Vaccine Inactivated Infectious Diseases Inactivated Poliovirus Vaccine Gambia Brief Reports sense organs business Life Sciences & Biomedicine
Zdroj:	Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
ISSN:	0184-7872 1058-4838
Popis:	The immunogenicity of fractional (one-fifth, 0.1 mL) intradermal doses of the inactivated poliovirus vaccine (ID fIPV) is positively correlated with the size of the intradermal fluid bleb. Training of vaccinators for campaign and routine ID fIPV administration should focus on generating an 8- to 10-mm bleb with each injection. Clinical Trials Registration NCT01847872
Databáze:	OpenAIRE
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